Product Information
NALBUPHINE 10 MG/ML AMPUL is a generic product labeled by Hospira Inc., priced at $4.3216 per ML under NDC 00409146301. Its NADAC has been published 36 times since Dec 17, 2025.
FDA first approved this application on Feb 3, 1989. Its Orange Book therapeutic-equivalence code is AP.
Strength
10 mg/mL
Manufacturer
Hospira Inc.NDC
00409146301
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Effective Date
3/18/2026
Active Ingredients
NALBUPHINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA070914FDA Approved
2/3/1989
TE Code
AP
On Market Since
6/27/2008
Pharmacological Classes
Price Statistics
The NADAC for NALBUPHINE 10 MG/ML AMPUL has been published 36 times since Dec 17, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $4.3216 per ML |
|---|---|
| All-time high | $4.3216 (Aug 19, 2026) |
| All-time low | $4.3216 (Dec 17, 2025) |
| 52-week high | $4.3216 |
| 52-week low | $4.3216 |
| Median price | $4.3216 |
| Average price | $4.3216 |
| Largest weekly change | 0.0% (Dec 24, 2025) |
| Weeks tracked | 36 |
| Tracking since | Dec 17, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NALBUPHINE 10 MG/ML AMPUL?
The current National Average Drug Acquisition Cost (NADAC) for NALBUPHINE 10 MG/ML AMPUL, manufactured by Hospira Inc., is $4.3216 per ML (NDC 00409146301), effective Aug 19, 2026.
How has the price of NALBUPHINE 10 MG/ML AMPUL changed over time?
Over the history we have for it, the NADAC for NALBUPHINE 10 MG/ML AMPUL has held within roughly two percent of its current level. It has been tracked across 36 weekly CMS publications since Dec 17, 2025.
What are the highest and lowest recorded NADAC prices for NALBUPHINE 10 MG/ML AMPUL?
Since Dec 17, 2025, the NADAC for NALBUPHINE 10 MG/ML AMPUL has ranged from a low of $4.3216 (Dec 17, 2025) to a high of $4.3216 (Aug 19, 2026), with a median of $4.3216 per ML.
Are there cheaper alternatives to NALBUPHINE 10 MG/ML AMPUL?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as NALBUPHINE 10 MG/ML AMPUL in a comparable dosage form, but none are currently priced below it.
Who manufactures NALBUPHINE 10 MG/ML AMPUL?
NALBUPHINE 10 MG/ML AMPUL (NDC 00409146301) is labeled by Hospira Inc., and CMS classifies it as a generic product.