Product Information

BUPRENORPHINE 2 MG TABLET SL is a generic product labeled by Advagen Pharma Ltd., priced at $0.2648 per EA under NDC 72888018230. Its NADAC has been published 103 times since Sep 4, 2024.

FDA first approved this application on Jun 10, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPRENORPHINE 2 MG TABLET SL

buprenorphine hydrochloride
$0.2648per EA
DEA Schedule CIII

Strength

2 mg/1

NDC

72888018230

Classification

Generic

Dosage Form

TABLET

Route

SUBLINGUAL

Effective Date

8/19/2026

Active Ingredients

BUPRENORPHINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA090279

FDA Approved

6/10/2015

TE Code

AB

On Market Since

6/10/2015

Pharmacological Classes

Partial Opioid Agonist
Partial Opioid Agonists

Price Statistics

The NADAC for BUPRENORPHINE 2 MG TABLET SL has been published 103 times since Sep 4, 2024, and over the history we have for it it has declined 57.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2648 per EA
All-time high$0.6289 (Sep 11, 2024)
All-time low$0.2629 (Jun 17, 2026)
52-week high$0.3179
52-week low$0.2629
Median price$0.3100
Average price$0.3358
Largest weekly change-32.7% (Nov 20, 2024)
Weeks tracked103
Tracking sinceSep 4, 2024

Price History

1W

-2.5%

1M

-2.5%

3M

-2.2%

6M

-10.7%

1Y

-16.7%

3Y

N/A

5Y

N/A

All

-57.9%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of BUPRENORPHINE 2 MG TABLET SL?

The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE 2 MG TABLET SL, manufactured by Advagen Pharma Ltd., is $0.2648 per EA (NDC 72888018230), effective Aug 19, 2026.

How has the price of BUPRENORPHINE 2 MG TABLET SL changed over time?

Over the history we have for it, the NADAC for BUPRENORPHINE 2 MG TABLET SL has declined 57.9%. It has been tracked across 103 weekly CMS publications since Sep 4, 2024.

What are the highest and lowest recorded NADAC prices for BUPRENORPHINE 2 MG TABLET SL?

Since Sep 4, 2024, the NADAC for BUPRENORPHINE 2 MG TABLET SL has ranged from a low of $0.2629 (Jun 17, 2026) to a high of $0.6289 (Sep 11, 2024), with a median of $0.3100 per EA.

Are there cheaper alternatives to BUPRENORPHINE 2 MG TABLET SL?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as BUPRENORPHINE 2 MG TABLET SL in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPRENORPHINE 2 MG TABLET SL?

BUPRENORPHINE 2 MG TABLET SL (NDC 72888018230) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.