Product Information

BUPRENORPHINE 2 MG TABLET SL is a generic product labeled by PAI Holdings LLC, priced at $0.2648 per EA under NDC 00121101930. Its NADAC has been published 129 times since Mar 6, 2024.

FDA first approved this application on Sep 24, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPRENORPHINE 2 MG TABLET SL

buprenorphine hydrochloride
$0.2648per EA
DEA Schedule CIII

Strength

2 mg/1

Manufacturer

PAI Holdings LLC

NDC

00121101930

Classification

Generic

Dosage Form

TABLET

Route

SUBLINGUAL

Effective Date

8/19/2026

Active Ingredients

BUPRENORPHINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA090622

FDA Approved

9/24/2010

TE Code

AB

On Market Since

10/12/2023

Pharmacological Classes

Partial Opioid Agonist
Partial Opioid Agonists

Price Statistics

The NADAC for BUPRENORPHINE 2 MG TABLET SL has been published 129 times since Mar 6, 2024, and over the history we have for it it has declined 41.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2648 per EA
All-time high$0.6289 (Sep 11, 2024)
All-time low$0.2629 (Jun 17, 2026)
52-week high$0.3179
52-week low$0.2629
Median price$0.3346
Average price$0.3645
Largest weekly change+42.0% (Aug 21, 2024)
Weeks tracked129
Tracking sinceMar 6, 2024

Price History

1W

-2.5%

1M

-2.5%

3M

-2.2%

6M

-10.7%

1Y

-16.7%

3Y

N/A

5Y

N/A

All

-41.0%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of BUPRENORPHINE 2 MG TABLET SL?

The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE 2 MG TABLET SL, manufactured by PAI Holdings LLC, is $0.2648 per EA (NDC 00121101930), effective Aug 19, 2026.

How has the price of BUPRENORPHINE 2 MG TABLET SL changed over time?

Over the history we have for it, the NADAC for BUPRENORPHINE 2 MG TABLET SL has declined 41.0%. It has been tracked across 129 weekly CMS publications since Mar 6, 2024.

What are the highest and lowest recorded NADAC prices for BUPRENORPHINE 2 MG TABLET SL?

Since Mar 6, 2024, the NADAC for BUPRENORPHINE 2 MG TABLET SL has ranged from a low of $0.2629 (Jun 17, 2026) to a high of $0.6289 (Sep 11, 2024), with a median of $0.3346 per EA.

Are there cheaper alternatives to BUPRENORPHINE 2 MG TABLET SL?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as BUPRENORPHINE 2 MG TABLET SL in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPRENORPHINE 2 MG TABLET SL?

BUPRENORPHINE 2 MG TABLET SL (NDC 00121101930) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.