Product Information
BUPRENORPHINE 2 MG TABLET SL is a generic product labeled by AvPAK, priced at $0.2768 per EA under NDC 50268012815. Its NADAC has been published 112 times since Aug 14, 2024.
FDA first approved this application on Jan 29, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2 mg/1
Manufacturer
AvPAKNDC
50268012815
Classification
Generic
Dosage Form
TABLET
Route
SUBLINGUAL
Effective Date
9/23/2026
Active Ingredients
BUPRENORPHINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA201760FDA Approved
1/29/2016
TE Code
AB
On Market Since
3/19/2024
Pharmacological Classes
Price Statistics
The NADAC for BUPRENORPHINE 2 MG TABLET SL has been published 112 times since Aug 14, 2024, and over the history we have for it it has declined 37.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2768 per EA |
|---|---|
| All-time high | $0.6289 (Sep 11, 2024) |
| All-time low | $0.2629 (Jun 17, 2026) |
| 52-week high | $0.3100 |
| 52-week low | $0.2629 |
| Median price | $0.3100 |
| Average price | $0.3384 |
| Largest weekly change | +42.0% (Aug 21, 2024) |
| Weeks tracked | 112 |
| Tracking since | Aug 14, 2024 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
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Drug market
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Therapeutic class
Partial Opioid Agonist class view
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Trend hub
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPRENORPHINE 2 MG TABLET SL?
The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE 2 MG TABLET SL, manufactured by AvPAK, is $0.2768 per EA (NDC 50268012815), effective Sep 30, 2026.
How has the price of BUPRENORPHINE 2 MG TABLET SL changed over time?
Over the history we have for it, the NADAC for BUPRENORPHINE 2 MG TABLET SL has declined 37.5%. It has been tracked across 112 weekly CMS publications since Aug 14, 2024.
What are the highest and lowest recorded NADAC prices for BUPRENORPHINE 2 MG TABLET SL?
Since Aug 14, 2024, the NADAC for BUPRENORPHINE 2 MG TABLET SL has ranged from a low of $0.2629 (Jun 17, 2026) to a high of $0.6289 (Sep 11, 2024), with a median of $0.3100 per EA.
Are there cheaper alternatives to BUPRENORPHINE 2 MG TABLET SL?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPRENORPHINE 2 MG TABLET SL in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPRENORPHINE 2 MG TABLET SL?
BUPRENORPHINE 2 MG TABLET SL (NDC 50268012815) is labeled by AvPAK, and CMS classifies it as a generic product.