Product Information

BUPRENORPHINE 2 MG TABLET SL is a generic product labeled by AvPAK, priced at $0.2648 per EA under NDC 50268012815. Its NADAC has been published 106 times since Aug 14, 2024.

FDA first approved this application on Jan 29, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPRENORPHINE 2 MG TABLET SL

Buprenorphine
$0.2648per EA
DEA Schedule CIII

Strength

2 mg/1

Manufacturer

AvPAK

NDC

50268012815

Classification

Generic

Dosage Form

TABLET

Route

SUBLINGUAL

Effective Date

8/19/2026

Active Ingredients

BUPRENORPHINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA201760

FDA Approved

1/29/2016

TE Code

AB

On Market Since

3/19/2024

Pharmacological Classes

Partial Opioid Agonist
Partial Opioid Agonists

Price Statistics

The NADAC for BUPRENORPHINE 2 MG TABLET SL has been published 106 times since Aug 14, 2024, and over the history we have for it it has declined 40.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2648 per EA
All-time high$0.6289 (Sep 11, 2024)
All-time low$0.2629 (Jun 17, 2026)
52-week high$0.3179
52-week low$0.2629
Median price$0.3140
Average price$0.3423
Largest weekly change+42.0% (Aug 21, 2024)
Weeks tracked106
Tracking sinceAug 14, 2024

Price History

1W

-2.5%

1M

-2.5%

3M

-2.2%

6M

-10.7%

1Y

-16.7%

3Y

N/A

5Y

N/A

All

-40.2%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPRENORPHINE 2 MG TABLET SL?

The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE 2 MG TABLET SL, manufactured by AvPAK, is $0.2648 per EA (NDC 50268012815), effective Aug 19, 2026.

How has the price of BUPRENORPHINE 2 MG TABLET SL changed over time?

Over the history we have for it, the NADAC for BUPRENORPHINE 2 MG TABLET SL has declined 40.2%. It has been tracked across 106 weekly CMS publications since Aug 14, 2024.

What are the highest and lowest recorded NADAC prices for BUPRENORPHINE 2 MG TABLET SL?

Since Aug 14, 2024, the NADAC for BUPRENORPHINE 2 MG TABLET SL has ranged from a low of $0.2629 (Jun 17, 2026) to a high of $0.6289 (Sep 11, 2024), with a median of $0.3140 per EA.

Are there cheaper alternatives to BUPRENORPHINE 2 MG TABLET SL?

5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPRENORPHINE 2 MG TABLET SL in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPRENORPHINE 2 MG TABLET SL?

BUPRENORPHINE 2 MG TABLET SL (NDC 50268012815) is labeled by AvPAK, and CMS classifies it as a generic product.