This NDC is on FDA's drug shortage list (posted Feb 22, 2012)
Product Information
LIDOCAINE HCL 2% 100 MG/5 ML is a generic product labeled by Hospira Inc., priced at $0.3487 per ML under NDC 00409206605. Its NADAC has been published 164 times since Sep 21, 2022.
FDA first approved this application on Jun 23, 1995. Its Orange Book therapeutic-equivalence code is AP.
Strength
20 mg/mL
Manufacturer
Hospira Inc.NDC
00409206605
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
EPIDURAL; INFILTRATION; INTRACAUDAL; PERINEURAL
Effective Date
7/22/2026
Active Ingredients
LIDOCAINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040078FDA Approved
6/23/1995
TE Code
AP
On Market Since
9/7/2005
Pharmacological Classes
Price Statistics
The NADAC for LIDOCAINE HCL 2% 100 MG/5 ML has been published 164 times since Sep 21, 2022, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3487 per ML |
|---|---|
| All-time high | $0.4109 (Feb 11, 2026) |
| All-time low | $0.3424 (Sep 21, 2022) |
| 52-week high | $0.4109 |
| 52-week low | $0.3487 |
| Median price | $0.3782 |
| Average price | $0.3733 |
| Largest weekly change | +15.4% (Apr 17, 2024) |
| Weeks tracked | 164 |
| Tracking since | Sep 21, 2022 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 78% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Hospira Inc. manufacturer profile
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Drug market
Lidocaine Hydrochloride market comparison
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Therapeutic class
Amide Local Anesthetic class view
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Trend hub
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LIDOCAINE HCL 2% 100 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE HCL 2% 100 MG/5 ML, manufactured by Hospira Inc., is $0.3487 per ML (NDC 00409206605), effective Sep 30, 2026.
How has the price of LIDOCAINE HCL 2% 100 MG/5 ML changed over time?
Over the history we have for it, the NADAC for LIDOCAINE HCL 2% 100 MG/5 ML has held within roughly two percent of its current level. It has been tracked across 164 weekly CMS publications since Sep 21, 2022.
What are the highest and lowest recorded NADAC prices for LIDOCAINE HCL 2% 100 MG/5 ML?
Since Sep 21, 2022, the NADAC for LIDOCAINE HCL 2% 100 MG/5 ML has ranged from a low of $0.3424 (Sep 21, 2022) to a high of $0.4109 (Feb 11, 2026), with a median of $0.3782 per ML.
Are there cheaper alternatives to LIDOCAINE HCL 2% 100 MG/5 ML?
Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LIDOCAINE HCL 2% VIAL, is $0.0762 per ML — about 78% below LIDOCAINE HCL 2% 100 MG/5 ML.
Who manufactures LIDOCAINE HCL 2% 100 MG/5 ML?
LIDOCAINE HCL 2% 100 MG/5 ML (NDC 00409206605) is labeled by Hospira Inc., and CMS classifies it as a generic product.
Is LIDOCAINE HCL 2% 100 MG/5 ML in shortage?
Yes — NDC 00409206605 is currently listed in FDA's drug shortage database (posted Feb 22, 2012).