Product Information
BYSTOLIC 2.5 MG TABLET is a brand product labeled by Allergan, Inc., priced at $6.4544 per EA under NDC 00456140230. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Dec 17, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/1
Manufacturer
Allergan, Inc.NDC
00456140230
Classification
Brand
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
NEBIVOLOL HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA021742FDA Approved
12/17/2007
TE Code
AB
On Market Since
1/22/2008
Pharmacological Classes
Price Statistics
The NADAC for BYSTOLIC 2.5 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 171.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $6.4544 per EA |
|---|---|
| All-time high | $6.4973 (Jun 10, 2026) |
| All-time low | $2.3786 (Nov 28, 2013) |
| 52-week high | $6.4973 |
| 52-week low | $6.1314 |
| Median price | $4.8021 |
| Average price | $4.6151 |
| Largest weekly change | +9.5% (Jan 9, 2019) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BYSTOLIC 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BYSTOLIC 2.5 MG TABLET, manufactured by Allergan, Inc., is $6.4544 per EA (NDC 00456140230), effective Aug 19, 2026.
How has the price of BYSTOLIC 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for BYSTOLIC 2.5 MG TABLET has risen 171.4%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for BYSTOLIC 2.5 MG TABLET?
Since Nov 28, 2013, the NADAC for BYSTOLIC 2.5 MG TABLET has ranged from a low of $2.3786 (Nov 28, 2013) to a high of $6.4973 (Jun 10, 2026), with a median of $4.8021 per EA.
Are there cheaper alternatives to BYSTOLIC 2.5 MG TABLET?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, NEBIVOLOL 2.5 MG TABLET, is $0.1189 per EA — about 98% below BYSTOLIC 2.5 MG TABLET.
Who manufactures BYSTOLIC 2.5 MG TABLET?
BYSTOLIC 2.5 MG TABLET (NDC 00456140230) is labeled by Allergan, Inc., and CMS classifies it as a brand product.