Product Information
CLOBETASOL 0.05% TOPICAL LOTN is a generic product labeled by Actavis Pharma, Inc., priced at $0.3381 per ML under NDC 00472040492. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Dec 4, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.05 g/100mL
Manufacturer
Actavis Pharma, Inc.NDC
00472040492
Classification
Generic
Dosage Form
LOTION
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA078223FDA Approved
12/4/2008
TE Code
AB
On Market Since
1/2/2012
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% TOPICAL LOTN has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 90.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3381 per ML |
|---|---|
| All-time high | $3.7449 (Feb 12, 2014) |
| All-time low | $0.1980 (Jul 17, 2024) |
| 52-week high | $0.3903 |
| 52-week low | $0.3197 |
| Median price | $1.0022 |
| Average price | $1.6419 |
| Largest weekly change | +66.7% (Oct 20, 2021) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 17% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% TOPICAL LOTN?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% TOPICAL LOTN, manufactured by Actavis Pharma, Inc., is $0.3381 per ML (NDC 00472040492), effective Aug 19, 2026.
How has the price of CLOBETASOL 0.05% TOPICAL LOTN changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% TOPICAL LOTN has declined 90.3%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% TOPICAL LOTN?
Since Nov 28, 2013, the NADAC for CLOBETASOL 0.05% TOPICAL LOTN has ranged from a low of $0.1980 (Jul 17, 2024) to a high of $3.7449 (Feb 12, 2014), with a median of $1.0022 per ML.
Are there cheaper alternatives to CLOBETASOL 0.05% TOPICAL LOTN?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% TOPICAL LOTN, is $0.2813 per ML — about 17% below CLOBETASOL 0.05% TOPICAL LOTN.
Who manufactures CLOBETASOL 0.05% TOPICAL LOTN?
CLOBETASOL 0.05% TOPICAL LOTN (NDC 00472040492) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.