Product Information
CLOBETASOL 0.05% TOPICAL LOTN is a generic product labeled by Actavis Pharma, Inc., priced at $0.3222 per ML under NDC 00472040492. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Dec 4, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.05 g/100mL
Manufacturer
Actavis Pharma, Inc.NDC
00472040492
Classification
Generic
Dosage Form
LOTION
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA078223FDA Approved
12/4/2008
TE Code
AB
On Market Since
1/2/2012
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% TOPICAL LOTN has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 90.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3222 per ML |
|---|---|
| All-time high | $3.7449 (Feb 12, 2014) |
| All-time low | $0.1980 (Jul 17, 2024) |
| 52-week high | $0.3903 |
| 52-week low | $0.3197 |
| Median price | $0.9846 |
| Average price | $1.6302 |
| Largest weekly change | +66.7% (Oct 20, 2021) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 14% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Actavis Pharma, Inc. manufacturer profile
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Drug market
Clobetasol Propionate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% TOPICAL LOTN?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% TOPICAL LOTN, manufactured by Actavis Pharma, Inc., is $0.3222 per ML (NDC 00472040492), effective Sep 30, 2026.
How has the price of CLOBETASOL 0.05% TOPICAL LOTN changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% TOPICAL LOTN has declined 90.7%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% TOPICAL LOTN?
Since Nov 28, 2013, the NADAC for CLOBETASOL 0.05% TOPICAL LOTN has ranged from a low of $0.1980 (Jul 17, 2024) to a high of $3.7449 (Feb 12, 2014), with a median of $0.9846 per ML.
Are there cheaper alternatives to CLOBETASOL 0.05% TOPICAL LOTN?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% TOPICAL LOTN, is $0.2755 per ML — about 14% below CLOBETASOL 0.05% TOPICAL LOTN.
Who manufactures CLOBETASOL 0.05% TOPICAL LOTN?
CLOBETASOL 0.05% TOPICAL LOTN (NDC 00472040492) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.