Product Information
CLOBETASOL 0.05% TOPICAL LOTN is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.2813 per ML under NDC 68180053602. Its NADAC has been published 444 times since Feb 21, 2018.
FDA first approved this application on Sep 22, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.05 g/100mL
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180053602
Classification
Generic
Dosage Form
LOTION
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA209147FDA Approved
9/22/2017
TE Code
AB
On Market Since
1/30/2018
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% TOPICAL LOTN has been published 444 times since Feb 21, 2018, and over the history we have for it it has declined 89.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2813 per ML |
|---|---|
| All-time high | $2.6465 (Apr 11, 2018) |
| All-time low | $0.2651 (Feb 18, 2026) |
| 52-week high | $0.3321 |
| 52-week low | $0.2651 |
| Median price | $0.5799 |
| Average price | $0.7950 |
| Largest weekly change | +85.2% (Dec 18, 2019) |
| Weeks tracked | 444 |
| Tracking since | Feb 21, 2018 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% TOPICAL LOTN?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% TOPICAL LOTN, manufactured by Lupin Pharmaceuticals Inc., is $0.2813 per ML (NDC 68180053602), effective Aug 19, 2026.
How has the price of CLOBETASOL 0.05% TOPICAL LOTN changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% TOPICAL LOTN has declined 89.4%. It has been tracked across 444 weekly CMS publications since Feb 21, 2018.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% TOPICAL LOTN?
Since Feb 21, 2018, the NADAC for CLOBETASOL 0.05% TOPICAL LOTN has ranged from a low of $0.2651 (Feb 18, 2026) to a high of $2.6465 (Apr 11, 2018), with a median of $0.5799 per ML.
Are there cheaper alternatives to CLOBETASOL 0.05% TOPICAL LOTN?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CLOBETASOL 0.05% TOPICAL LOTN in a comparable dosage form, but none are currently priced below it.
Who manufactures CLOBETASOL 0.05% TOPICAL LOTN?
CLOBETASOL 0.05% TOPICAL LOTN (NDC 68180053602) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.