Product Information

SPIRONOLACTONE 25 MG/5 ML SUSP is a generic product labeled by Padagis US LLC, priced at $1.8338 per ML under NDC 00574113316. Its NADAC has been published 40 times since Nov 19, 2025.

FDA first approved this application on Aug 4, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the spironolactone market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

SPIRONOLACTONE 25 MG/5 ML SUSP

spironolactone
$1.8338per ML
High Outlier

Strength

25 mg/5mL

Manufacturer

Padagis US LLC

NDC

00574113316

Classification

Generic

Dosage Form

SUSPENSION

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SPIRONOLACTONE

Approval Type

Authorized Generic (NDA)

FDA Application

NDA209478

FDA Approved

8/4/2017

TE Code

AB

On Market Since

10/31/2023

Pharmacological Classes

Aldosterone Antagonist
Aldosterone Antagonists

Price Statistics

The NADAC for SPIRONOLACTONE 25 MG/5 ML SUSP has been published 40 times since Nov 19, 2025, and over the history we have for it it has risen 19.4%. The table below summarizes its recorded NADAC range and movement.

Current price$1.8338 per ML
All-time high$1.8338 (Aug 19, 2026)
All-time low$1.5255 (Dec 17, 2025)
52-week high$1.8338
52-week low$1.5255
Median price$1.6595
Average price$1.6548
Largest weekly change+5.9% (Mar 18, 2026)
Weeks tracked40
Tracking sinceNov 19, 2025

Price History

1W

+2.3%

1M

+2.3%

3M

+5.0%

6M

+17.1%

1Y

N/A

3Y

N/A

5Y

N/A

All

+19.4%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 15% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SPIRONOLACTONE 25 MG/5 ML SUSP?

The current National Average Drug Acquisition Cost (NADAC) for SPIRONOLACTONE 25 MG/5 ML SUSP, manufactured by Padagis US LLC, is $1.8338 per ML (NDC 00574113316), effective Aug 19, 2026.

How has the price of SPIRONOLACTONE 25 MG/5 ML SUSP changed over time?

Over the history we have for it, the NADAC for SPIRONOLACTONE 25 MG/5 ML SUSP has risen 19.4%. It has been tracked across 40 weekly CMS publications since Nov 19, 2025.

What are the highest and lowest recorded NADAC prices for SPIRONOLACTONE 25 MG/5 ML SUSP?

Since Nov 19, 2025, the NADAC for SPIRONOLACTONE 25 MG/5 ML SUSP has ranged from a low of $1.5255 (Dec 17, 2025) to a high of $1.8338 (Aug 19, 2026), with a median of $1.6595 per ML.

Are there cheaper alternatives to SPIRONOLACTONE 25 MG/5 ML SUSP?

Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SPIRONOLACTONE 25 MG/5 ML SUSP, is $1.5664 per ML — about 15% below SPIRONOLACTONE 25 MG/5 ML SUSP.

Who manufactures SPIRONOLACTONE 25 MG/5 ML SUSP?

SPIRONOLACTONE 25 MG/5 ML SUSP (NDC 00574113316) is labeled by Padagis US LLC, and CMS classifies it as a generic product.