Product Information
ACYCLOVIR 5% OINTMENT is a generic product labeled by Actavis Pharma, Inc., priced at $0.3149 per GM under NDC 00591115930. Its NADAC has been published 634 times since May 14, 2014.
FDA first approved this application on Mar 29, 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/g
Manufacturer
Actavis Pharma, Inc.NDC
00591115930
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
6/17/2026
Active Ingredients
ACYCLOVIRApproval Type
Authorized Generic (NDA)
FDA Application
NDA018604FDA Approved
3/29/1982
TE Code
AB
On Market Since
4/11/2014
Pharmacological Classes
Price Statistics
The NADAC for ACYCLOVIR 5% OINTMENT has been published 634 times since May 14, 2014, and over the history we have for it it has declined 98.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3149 per GM |
|---|---|
| All-time high | $17.3294 (Aug 13, 2014) |
| All-time low | $0.3146 (Apr 22, 2026) |
| 52-week high | $0.4109 |
| 52-week low | $0.3146 |
| Median price | $1.6031 |
| Average price | $4.7109 |
| Largest weekly change | +89.1% (Jun 23, 2021) |
| Weeks tracked | 634 |
| Tracking since | May 14, 2014 |
1W
N/A
1M
N/A
3M
N/A
6M
-1.8%
1Y
-23.4%
3Y
-43.5%
5Y
-80.4%
All
-98.2%
Last surveyed Jul 1, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Actavis Pharma, Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
acyclovir market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ACYCLOVIR 5% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 5% OINTMENT, manufactured by Actavis Pharma, Inc., is $0.3149 per GM (NDC 00591115930), effective Jul 1, 2026.
How has the price of ACYCLOVIR 5% OINTMENT changed over time?
Over the history we have for it, the NADAC for ACYCLOVIR 5% OINTMENT has declined 98.2%. It has been tracked across 634 weekly CMS publications since May 14, 2014.
What are the highest and lowest recorded NADAC prices for ACYCLOVIR 5% OINTMENT?
Since May 14, 2014, the NADAC for ACYCLOVIR 5% OINTMENT has ranged from a low of $0.3146 (Apr 22, 2026) to a high of $17.3294 (Aug 13, 2014), with a median of $1.6031 per GM.
Are there cheaper alternatives to ACYCLOVIR 5% OINTMENT?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ACYCLOVIR 5% OINTMENT in a comparable dosage form, but none are currently priced below it.
Who manufactures ACYCLOVIR 5% OINTMENT?
ACYCLOVIR 5% OINTMENT (NDC 00591115930) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.