Product Information

ACYCLOVIR 5% OINTMENT is a generic product labeled by Actavis Pharma, Inc., priced at $0.3149 per GM under NDC 00591115930. Its NADAC has been published 634 times since May 14, 2014.

FDA first approved this application on Mar 29, 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ACYCLOVIR 5% OINTMENT

acyclovir
$0.3149per GM

Strength

50 mg/g

NDC

00591115930

Classification

Generic

Dosage Form

OINTMENT

Route

TOPICAL

Effective Date

6/17/2026

Active Ingredients

ACYCLOVIR

Approval Type

Authorized Generic (NDA)

FDA Application

NDA018604

FDA Approved

3/29/1982

TE Code

AB

On Market Since

4/11/2014

Price Statistics

The NADAC for ACYCLOVIR 5% OINTMENT has been published 634 times since May 14, 2014, and over the history we have for it it has declined 98.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3149 per GM
All-time high$17.3294 (Aug 13, 2014)
All-time low$0.3146 (Apr 22, 2026)
52-week high$0.4469
52-week low$0.3146
Median price$1.6031
Average price$4.7109
Largest weekly change+89.1% (Jun 23, 2021)
Weeks tracked634
Tracking sinceMay 14, 2014

Price History

1W

N/A

1M

N/A

3M

-2.9%

6M

-4.0%

1Y

-29.5%

3Y

-59.3%

5Y

-74.3%

All

-98.2%

Last surveyed Jul 1, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ACYCLOVIR 5% OINTMENT?

The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 5% OINTMENT, manufactured by Actavis Pharma, Inc., is $0.3149 per GM (NDC 00591115930), effective Jul 1, 2026.

How has the price of ACYCLOVIR 5% OINTMENT changed over time?

Over the history we have for it, the NADAC for ACYCLOVIR 5% OINTMENT has declined 98.2%. It has been tracked across 634 weekly CMS publications since May 14, 2014.

What are the highest and lowest recorded NADAC prices for ACYCLOVIR 5% OINTMENT?

Since May 14, 2014, the NADAC for ACYCLOVIR 5% OINTMENT has ranged from a low of $0.3146 (Apr 22, 2026) to a high of $17.3294 (Aug 13, 2014), with a median of $1.6031 per GM.

Are there cheaper alternatives to ACYCLOVIR 5% OINTMENT?

5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ACYCLOVIR 5% OINTMENT in a comparable dosage form, but none are currently priced below it.

Who manufactures ACYCLOVIR 5% OINTMENT?

ACYCLOVIR 5% OINTMENT (NDC 00591115930) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.