Product Information
METHYLPREDNISOLONE 4 MG DOSEPK is a generic product labeled by Endo USA Inc., priced at $0.1361 per EA under NDC 00603459315. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Dec 22, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
4 mg/1
Manufacturer
Endo USA Inc.NDC
00603459315
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
METHYLPREDNISOLONEApproval Type
Generic (ANDA)
FDA Application
ANDA040183FDA Approved
12/22/1998
TE Code
AB
On Market Since
12/22/1998
Pharmacological Classes
Price Statistics
The NADAC for METHYLPREDNISOLONE 4 MG DOSEPK has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 83.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1361 per EA |
|---|---|
| All-time high | $0.8134 (Dec 11, 2013) |
| All-time low | $0.0962 (Nov 20, 2024) |
| 52-week high | $0.1361 |
| 52-week low | $0.1124 |
| Median price | $0.2258 |
| Average price | $0.3182 |
| Largest weekly change | -31.4% (Nov 20, 2024) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 11% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Endo USA Inc. manufacturer profile
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Drug market
methylprednisolone market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METHYLPREDNISOLONE 4 MG DOSEPK?
The current National Average Drug Acquisition Cost (NADAC) for METHYLPREDNISOLONE 4 MG DOSEPK, manufactured by Endo USA Inc., is $0.1361 per EA (NDC 00603459315), effective Sep 30, 2026.
How has the price of METHYLPREDNISOLONE 4 MG DOSEPK changed over time?
Over the history we have for it, the NADAC for METHYLPREDNISOLONE 4 MG DOSEPK has declined 83.3%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for METHYLPREDNISOLONE 4 MG DOSEPK?
Since Nov 28, 2013, the NADAC for METHYLPREDNISOLONE 4 MG DOSEPK has ranged from a low of $0.0962 (Nov 20, 2024) to a high of $0.8134 (Dec 11, 2013), with a median of $0.2258 per EA.
Are there cheaper alternatives to METHYLPREDNISOLONE 4 MG DOSEPK?
Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METHYLPREDNISOLONE 4 MG TABLET, is $0.1211 per EA — about 11% below METHYLPREDNISOLONE 4 MG DOSEPK.
Who manufactures METHYLPREDNISOLONE 4 MG DOSEPK?
METHYLPREDNISOLONE 4 MG DOSEPK (NDC 00603459315) is labeled by Endo USA Inc., and CMS classifies it as a generic product.