Product Information
METHYLPREDNISOLONE 4 MG TABLET is a generic product labeled by Endo USA Inc., priced at $0.1240 per EA under NDC 00603459321. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Dec 22, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
4 mg/1
Manufacturer
Endo USA Inc.NDC
00603459321
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METHYLPREDNISOLONEApproval Type
Generic (ANDA)
FDA Application
ANDA040183FDA Approved
12/22/1998
TE Code
AB
On Market Since
12/22/1998
Pharmacological Classes
Price Statistics
The NADAC for METHYLPREDNISOLONE 4 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 87.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1240 per EA |
|---|---|
| All-time high | $1.0196 (Apr 16, 2014) |
| All-time low | $0.1105 (Nov 20, 2024) |
| 52-week high | $0.1606 |
| 52-week low | $0.1211 |
| Median price | $0.2277 |
| Average price | $0.3997 |
| Largest weekly change | -34.6% (Mar 21, 2018) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METHYLPREDNISOLONE 4 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHYLPREDNISOLONE 4 MG TABLET, manufactured by Endo USA Inc., is $0.1240 per EA (NDC 00603459321), effective Aug 19, 2026.
How has the price of METHYLPREDNISOLONE 4 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHYLPREDNISOLONE 4 MG TABLET has declined 87.3%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for METHYLPREDNISOLONE 4 MG TABLET?
Since Nov 28, 2013, the NADAC for METHYLPREDNISOLONE 4 MG TABLET has ranged from a low of $0.1105 (Nov 20, 2024) to a high of $1.0196 (Apr 16, 2014), with a median of $0.2277 per EA.
Are there cheaper alternatives to METHYLPREDNISOLONE 4 MG TABLET?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHYLPREDNISOLONE 4 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures METHYLPREDNISOLONE 4 MG TABLET?
METHYLPREDNISOLONE 4 MG TABLET (NDC 00603459321) is labeled by Endo USA Inc., and CMS classifies it as a generic product.