This NDC is on FDA's drug shortage list (posted Dec 20, 2023)
Reported reason: Demand increase for the drug
Product Information
FENTANYL 100 MCG/2 ML VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $1.7269 per ML under NDC 00641602725. Its NADAC has been published 570 times since Nov 28, 2013.
FDA first approved this application on Jul 11, 1984. Its Orange Book therapeutic-equivalence code is AP.
The Low Outlier badge above means this manufacturer's average price in the Fentanyl Citrate market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 ug/mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00641602725
Classification
Generic
Dosage Form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
FENTANYL CITRATEApproval Type
New Drug (NDA)
FDA Application
NDA019101FDA Approved
7/11/1984
TE Code
AP
On Market Since
7/11/1984
Pharmacological Classes
Price Statistics
The NADAC for FENTANYL 100 MCG/2 ML VIAL has been published 570 times since Nov 28, 2013, and over the history we have for it it has risen 237.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.7269 per ML |
|---|---|
| All-time high | $1.7269 (Aug 19, 2026) |
| All-time low | $0.3568 (Nov 19, 2014) |
| 52-week high | $1.7269 |
| 52-week low | $0.8723 |
| Median price | $0.6264 |
| Average price | $0.6537 |
| Largest weekly change | +82.4% (Jun 20, 2018) |
| Weeks tracked | 570 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 65% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of FENTANYL 100 MCG/2 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for FENTANYL 100 MCG/2 ML VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $1.7269 per ML (NDC 00641602725), effective Aug 19, 2026.
How has the price of FENTANYL 100 MCG/2 ML VIAL changed over time?
Over the history we have for it, the NADAC for FENTANYL 100 MCG/2 ML VIAL has risen 237.7%. It has been tracked across 570 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for FENTANYL 100 MCG/2 ML VIAL?
Since Nov 28, 2013, the NADAC for FENTANYL 100 MCG/2 ML VIAL has ranged from a low of $0.3568 (Nov 19, 2014) to a high of $1.7269 (Aug 19, 2026), with a median of $0.6264 per ML.
Are there cheaper alternatives to FENTANYL 100 MCG/2 ML VIAL?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FENTANYL 1,000 MCG/20 ML AMPUL, is $0.5981 per ML — about 65% below FENTANYL 100 MCG/2 ML VIAL.
Who manufactures FENTANYL 100 MCG/2 ML VIAL?
FENTANYL 100 MCG/2 ML VIAL (NDC 00641602725) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.
Is FENTANYL 100 MCG/2 ML VIAL in shortage?
Yes — NDC 00641602725 is currently listed in FDA's drug shortage database (posted Dec 20, 2023). Reported reason: Demand increase for the drug.