Product Information
BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $2.5966 per ML under NDC 00832142510. Its NADAC has been published 162 times since May 24, 2023.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Upsher-Smith Laboratories LLCNDC
00832142510
Classification
Generic
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Last Updated
6/17/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
Generic (ANDA)
FDA Application
ANDA215598On Market Since
12/15/2022
Pharmacological Classes
Price Statistics
The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 162 times since May 24, 2023, and over the history we have for it it has declined 86.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.5966 per ML |
|---|---|
| All-time high | $19.2842 (Jun 14, 2023) |
| All-time low | $2.3704 (May 20, 2026) |
| 52-week high | $5.6921 |
| 52-week low | $2.3704 |
| Median price | $8.5910 |
| Average price | $9.2601 |
| Largest weekly change | +56.9% (May 22, 2024) |
| Weeks tracked | 162 |
| Tracking since | May 24, 2023 |
Generic Alternatives
The matcher finds 8 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 8 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 19% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?
The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Upsher-Smith Laboratories LLC, is $2.5966 per ML (NDC 00832142510), effective Jun 24, 2026.
How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?
Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 86.5%. It has been tracked across 162 weekly CMS publications since May 24, 2023.
What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Since May 24, 2023, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $2.3704 (May 20, 2026) to a high of $19.2842 (Jun 14, 2023), with a median of $8.5910 per ML.
Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Yes. 8 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, BRIMONIDINE-TIMOLOL 0.2%-0.5%, is $2.1018 per ML — about 19% below BRIMONIDINE-TIMOLOL 0.2%-0.5%.
Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?
BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 00832142510) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.
Related Drugs
Same classification