Product Information

BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Glenmark Pharmaceuticals Inc., USA, priced at $2.4609 per ML under NDC 68462028132. Its NADAC has been published 112 times since Jul 3, 2024.

FDA first approved this application on May 16, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Brimonidine Tartrate and Timolol Maleate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

BRIMONIDINE-TIMOLOL 0.2%-0.5%

Brimonidine Tartrate and Timolol Maleate
$2.4609per ML
High Outlier

Strength

2; 5 mg/mL; mg/mL

NDC

68462028132

Classification

Generic

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA214987

FDA Approved

5/16/2024

TE Code

AB

On Market Since

5/16/2024

Pharmacological Classes

Adrenergic alpha-Agonists
Adrenergic beta-Antagonists
alpha-Adrenergic Agonist
beta-Adrenergic Blocker

Price Statistics

The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 112 times since Jul 3, 2024, and over the history we have for it it has declined 73.3%. The table below summarizes its recorded NADAC range and movement.

Current price$2.4609 per ML
All-time high$11.4034 (Sep 11, 2024)
All-time low$2.3704 (May 20, 2026)
52-week high$4.6326
52-week low$2.3704
Median price$5.0994
Average price$5.7375
Largest weekly change+32.4% (Oct 23, 2024)
Weeks tracked112
Tracking sinceJul 3, 2024

Price History

1W

-8.0%

1M

-8.0%

3M

+3.8%

6M

-11.4%

1Y

-46.9%

3Y

N/A

5Y

N/A

All

-73.3%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 25% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?

The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Glenmark Pharmaceuticals Inc., USA, is $2.4609 per ML (NDC 68462028132), effective Aug 19, 2026.

How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?

Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 73.3%. It has been tracked across 112 weekly CMS publications since Jul 3, 2024.

What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?

Since Jul 3, 2024, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $2.3704 (May 20, 2026) to a high of $11.4034 (Sep 11, 2024), with a median of $5.0994 per ML.

Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BRIMONIDINE-TIMOLOL 0.2%-0.5%, is $1.8390 per ML — about 25% below BRIMONIDINE-TIMOLOL 0.2%-0.5%.

Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?

BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 68462028132) is labeled by Glenmark Pharmaceuticals Inc., USA, and CMS classifies it as a generic product.