Product Information
DIPHENHYDRAMINE 50 MG CAPSULE is a generic product labeled by Major Pharmaceuticals, priced at $0.0316 per EA under NDC 00904205661. Its NADAC has been published 657 times since Nov 28, 2013.
Strength
50 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904205661
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
1/2/2009
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 50 MG CAPSULE has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 60.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0316 per EA |
|---|---|
| All-time high | $0.0316 (Jun 24, 2026) |
| All-time low | $0.0176 (May 19, 2021) |
| 52-week high | $0.0316 |
| 52-week low | $0.0219 |
| Median price | $0.0224 |
| Average price | $0.0223 |
| Largest weekly change | +35.2% (Feb 23, 2022) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 22% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 50 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 50 MG CAPSULE, manufactured by Major Pharmaceuticals, is $0.0316 per EA (NDC 00904205661), effective Jun 24, 2026.
How has the price of DIPHENHYDRAMINE 50 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 50 MG CAPSULE has risen 60.5%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 50 MG CAPSULE?
Since Nov 28, 2013, the NADAC for DIPHENHYDRAMINE 50 MG CAPSULE has ranged from a low of $0.0176 (May 19, 2021) to a high of $0.0316 (Jun 24, 2026), with a median of $0.0224 per EA.
Are there cheaper alternatives to DIPHENHYDRAMINE 50 MG CAPSULE?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, DIPHENHYDRAMINE 50 MG CAPSULE, is $0.0246 per EA — about 22% below DIPHENHYDRAMINE 50 MG CAPSULE.
Who manufactures DIPHENHYDRAMINE 50 MG CAPSULE?
DIPHENHYDRAMINE 50 MG CAPSULE (NDC 00904205661) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.
Related Drugs
Same classification