Product Information

DONEPEZIL HCL 5 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0435 per EA under NDC 00904647761. Its NADAC has been published 442 times since Mar 7, 2018.

FDA first approved this application on May 31, 2011. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DONEPEZIL HCL 5 MG TABLET

Donepezil Hydrochloride
$0.0435per EA

Strength

5 mg/1

NDC

00904647761

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

DONEPEZIL HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA090686

FDA Approved

5/31/2011

TE Code

AB

On Market Since

5/28/2011

Pharmacological Classes

Cholinesterase Inhibitor
Cholinesterase Inhibitors

Price Statistics

The NADAC for DONEPEZIL HCL 5 MG TABLET has been published 442 times since Mar 7, 2018, and over the history we have for it it has declined 27.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0435 per EA
All-time high$0.0603 (Mar 14, 2018)
All-time low$0.0334 (May 22, 2024)
52-week high$0.0446
52-week low$0.0424
Median price$0.0486
Average price$0.0486
Largest weekly change+28.3% (Nov 22, 2023)
Weeks tracked442
Tracking sinceMar 7, 2018

Price History

1W

+0.6%

1M

+0.6%

3M

-0.7%

6M

-2.5%

1Y

-2.2%

3Y

+3.8%

5Y

-23.9%

All

-27.9%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DONEPEZIL HCL 5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for DONEPEZIL HCL 5 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0435 per EA (NDC 00904647761), effective Aug 19, 2026.

How has the price of DONEPEZIL HCL 5 MG TABLET changed over time?

Over the history we have for it, the NADAC for DONEPEZIL HCL 5 MG TABLET has declined 27.9%. It has been tracked across 442 weekly CMS publications since Mar 7, 2018.

What are the highest and lowest recorded NADAC prices for DONEPEZIL HCL 5 MG TABLET?

Since Mar 7, 2018, the NADAC for DONEPEZIL HCL 5 MG TABLET has ranged from a low of $0.0334 (May 22, 2024) to a high of $0.0603 (Mar 14, 2018), with a median of $0.0486 per EA.

Are there cheaper alternatives to DONEPEZIL HCL 5 MG TABLET?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DONEPEZIL HCL 5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures DONEPEZIL HCL 5 MG TABLET?

DONEPEZIL HCL 5 MG TABLET (NDC 00904647761) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.