Drug Markets/Donepezil Hydrochloride

Donepezil Hydrochloride

85 NDCs across 17 manufacturers|82 Generic,3 Brand

Donepezil Hydrochloride is used to treat alzheimer disease, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Nov 25, 1996, and the first generic was approved Dec 11, 2009. FDA's Orange Book lists 42 AB-rated (therapeutically equivalent) products for this ingredient.

Donepezil Hydrochloride is available as 85 NDCs from 17 manufacturers (82 generic, 3 brand), with NADAC prices from $0.04 to $16.44 per EA — the most expensive product costs about 375× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

82G / 3B

Manufacturers

competing in market

Price Spread

$0.04 – $16.44

per EA

7d Activity

61↑1↓23 flat

avg +0.8% WoW · of 85 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Explore this market from other angles

Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.

Top supplier

Macleods Pharmaceuticals Limited manufacturer profile

Open the supplier page for the manufacturer with the strongest footprint in this market.

Lead class

Cholinesterase Inhibitor class view

See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.

Trend hub

Latest market trends

Move from this single molecule into the current cross-market mover and volatility view.

Guide

How to interpret NADAC

Review the benchmark methodology behind the prices and spreads shown on this market page.

Manufacturer Breakdown

17 manufacturers producing DONEPEZIL HYDROCHLORIDE(4 pricing outliers)

Macleods Pharmaceuticals Limited

14 NDCs

$0.2134

avg/unit

Torrent Pharmaceuticals Limited

8 NDCs

$0.0467

avg/unit

ACI Healthcare USA, Inc.

8 NDCs

$0.0462

avg/unit

Rising Pharma Holdings Inc.

8 NDCs

$0.0462

avg/unit

Dr. Reddy's Laboratories Inc.

6 NDCs

$0.2756

avg/unit

Aurobindo Pharma Limited

6 NDCs

$0.0620

avg/unit

Camber Pharmaceuticals Inc.

6 NDCs

$0.0462

avg/unit

Solco Healthcare US LLC

6 NDCs

$0.0462

avg/unit

Alembic Pharmaceuticals Inc.

Lupin Pharmaceuticals Inc.

Edenbridge Pharmaceuticals LLC

Upsher-Smith Laboratories LLC

Unichem Pharmaceuticals (USA) Inc.

2 NDCs

$0.2671

avg/unit

Major Pharmaceuticals

2 NDCs

$0.0462

avg/unit

American Health Packaging

2 NDCs

$0.0462

avg/unit

Quallent Pharmaceuticals Health LLC

2 NDCs

$0.0462

avg/unit

Drug Portfolio

85 NDCs total, 85 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
ARICEPT 5 MG TABLET	62856024530	Eisai Inc.	$16.4368 per EA	High Outlier	Brand	—	Cholinesterase Inhibitor
ARICEPT 10 MG TABLET	62856024630	Eisai Inc.	$16.1969 per EA	High Outlier	Brand	—	Cholinesterase Inhibitor
ARICEPT 23 MG TABLET	62856024730	Eisai Inc.	$14.3864 per EA	High Outlier	Brand	—	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	68180052709	Lupin Pharmaceuticals Inc.	$0.7936 per EA	High Outlier	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	68180052706	Lupin Pharmaceuticals Inc.	$0.7936 per EA	High Outlier	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	42799095402	Edenbridge Pharmaceuticals LLC	$0.7354 per EA	High Outlier	Generic	+0.86%	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	55111030230	Dr. Reddy's Laboratories Inc.	$0.7354 per EA	—	Generic	+0.86%	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	24979000406	Upsher-Smith Laboratories LLC	$0.7354 per EA	High Outlier	Generic	+0.86%	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	24979000407	Upsher-Smith Laboratories LLC	$0.7354 per EA	High Outlier	Generic	+0.86%	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	55111030290	Dr. Reddy's Laboratories Inc.	$0.7354 per EA	—	Generic	+0.86%	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	33342006107	Macleods Pharmaceuticals Limited	$0.7354 per EA	—	Generic	+0.86%	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	33342006110	Macleods Pharmaceuticals Limited	$0.7354 per EA	—	Generic	+0.86%	Cholinesterase Inhibitor
DONEPEZIL HCL 23 MG TABLET	42799095401	Edenbridge Pharmaceuticals LLC	$0.7354 per EA	High Outlier	Generic	+0.86%	Cholinesterase Inhibitor
DONEPEZIL HCL ODT 10 MG TABLET	33342003060	Macleods Pharmaceuticals Limited	$0.3087 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL ODT 10 MG TABLET	33342003007	Macleods Pharmaceuticals Limited	$0.2912 per EA	—	Generic	+2.45%	Cholinesterase Inhibitor
DONEPEZIL HCL ODT 5 MG TABLET	33342002907	Macleods Pharmaceuticals Limited	$0.2807 per EA	—	Generic	-3.79%	Cholinesterase Inhibitor
DONEPEZIL HCL ODT 5 MG TABLET	29300025087	Unichem Pharmaceuticals (USA) Inc.	$0.2673 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL ODT 10 MG TABLET	29300025187	Unichem Pharmaceuticals (USA) Inc.	$0.2668 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL ODT 5 MG TABLET	33342002960	Macleods Pharmaceuticals Limited	$0.2638 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	65862032630	Aurobindo Pharma Limited	$0.0712 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	65862032599	Aurobindo Pharma Limited	$0.0633 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	65862032530	Aurobindo Pharma Limited	$0.0633 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	65862032590	Aurobindo Pharma Limited	$0.0633 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	65862032699	Aurobindo Pharma Limited	$0.0554 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	65862032690	Aurobindo Pharma Limited	$0.0554 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	33342002844	Macleods Pharmaceuticals Limited	$0.0505 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	13668010326	Torrent Pharmaceuticals Limited	$0.0492 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	71093012803	ACI Healthcare USA, Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	00904647861	Major Pharmaceuticals	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	13668010310	Torrent Pharmaceuticals Limited	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	13668010330	Torrent Pharmaceuticals Limited	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	13668010390	Torrent Pharmaceuticals Limited	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	16571077903	Rising Pharma Holdings Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	16571077909	Rising Pharma Holdings Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	16571077910	Rising Pharma Holdings Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	16571077950	Rising Pharma Holdings Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	31722073805	Camber Pharmaceuticals Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	31722073830	Camber Pharmaceuticals Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	31722073890	Camber Pharmaceuticals Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	33342002807	Macleods Pharmaceuticals Limited	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	33342002810	Macleods Pharmaceuticals Limited	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	33342002815	Macleods Pharmaceuticals Limited	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	43547027603	Solco Healthcare US LLC	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	43547027609	Solco Healthcare US LLC	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	43547027611	Solco Healthcare US LLC	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	60687030301	American Health Packaging	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	71093012801	ACI Healthcare USA, Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	82009012005	Quallent Pharmaceuticals Health LLC	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	71093012806	ACI Healthcare USA, Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	62332009330	Alembic Pharmaceuticals Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	62332009390	Alembic Pharmaceuticals Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	62332009391	Alembic Pharmaceuticals Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	71093012805	ACI Healthcare USA, Inc.	$0.0484 per EA	—	Generic	+0.62%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	13668010240	Torrent Pharmaceuticals Limited	$0.0476 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	55111035705	Dr. Reddy's Laboratories Inc.	$0.0476 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 10 MG TABLET	55111035710	Dr. Reddy's Laboratories Inc.	$0.0476 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	33342002744	Macleods Pharmaceuticals Limited	$0.0450 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	71093012703	ACI Healthcare USA, Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	71093012701	ACI Healthcare USA, Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	62332009291	Alembic Pharmaceuticals Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	82009011905	Quallent Pharmaceuticals Health LLC	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	62332009290	Alembic Pharmaceuticals Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	62332009230	Alembic Pharmaceuticals Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	60687029201	American Health Packaging	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	43547027511	Solco Healthcare US LLC	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	43547027509	Solco Healthcare US LLC	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	71093012706	ACI Healthcare USA, Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	13668010210	Torrent Pharmaceuticals Limited	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	71093012705	ACI Healthcare USA, Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	43547027503	Solco Healthcare US LLC	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	33342002715	Macleods Pharmaceuticals Limited	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	33342002710	Macleods Pharmaceuticals Limited	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	33342002707	Macleods Pharmaceuticals Limited	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	31722073790	Camber Pharmaceuticals Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	00904647761	Major Pharmaceuticals	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	31722073730	Camber Pharmaceuticals Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	31722073705	Camber Pharmaceuticals Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	16571077850	Rising Pharma Holdings Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	16571077810	Rising Pharma Holdings Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	16571077809	Rising Pharma Holdings Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	16571077803	Rising Pharma Holdings Inc.	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	13668010290	Torrent Pharmaceuticals Limited	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	13668010230	Torrent Pharmaceuticals Limited	$0.0440 per EA	—	Generic	+1.06%	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	55111035610	Dr. Reddy's Laboratories Inc.	$0.0438 per EA	—	Generic	—	Cholinesterase Inhibitor
DONEPEZIL HCL 5 MG TABLET	55111035605	Dr. Reddy's Laboratories Inc.	$0.0438 per EA	—	Generic	—	Cholinesterase Inhibitor

Frequently Asked Questions

What is Donepezil Hydrochloride used to treat?

Donepezil Hydrochloride is used to treat alzheimer disease, per the National Library of Medicine's MED-RT classification.

When did Donepezil Hydrochloride become available as a generic?

FDA approved the first generic Donepezil Hydrochloride (ANDA) on Dec 11, 2009. The Orange Book currently lists 42 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How many Donepezil Hydrochloride products are on the market?

The Donepezil Hydrochloride drug market contains 85 NDCs from 17 manufacturers — 82 generic and 3 brand products.

What is the price range for Donepezil Hydrochloride?

NADAC reference prices for Donepezil Hydrochloride range from $0.0438 to $16.4368 per EA — the most expensive product costs about 375× the cheapest.

Is generic Donepezil Hydrochloride cheaper than brand?

The average generic NADAC for Donepezil Hydrochloride is $0.1500 per EA, versus $15.6734 for brand-labeled products — brand versions average about 105× the generic price.

Which manufacturers make Donepezil Hydrochloride?

17 manufacturers list Donepezil Hydrochloride in NADAC. Ranked by number of NDCs, the largest are Macleods Pharmaceuticals Limited (14), Torrent Pharmaceuticals Limited (8), ACI Healthcare USA, Inc. (8), Rising Pharma Holdings Inc. (8), Dr. Reddy's Laboratories Inc. (6).

How has the price of Donepezil Hydrochloride changed recently?

Over the past 7 days, 61 Donepezil Hydrochloride NDCs rose and 1 fell, with a market-wide average change of +0.8%.