Product Information
ONDANSETRON HCL 8 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0781 per EA under NDC 00904655261. Its NADAC has been published 535 times since Jul 6, 2016.
FDA first approved this application on Dec 26, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
8 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904655261
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ONDANSETRON HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA076183FDA Approved
12/26/2006
TE Code
AB
On Market Since
12/26/2006
Pharmacological Classes
Price Statistics
The NADAC for ONDANSETRON HCL 8 MG TABLET has been published 535 times since Jul 6, 2016, and over the history we have for it it has declined 69.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0781 per EA |
|---|---|
| All-time high | $0.2814 (Sep 14, 2016) |
| All-time low | $0.0715 (Nov 20, 2024) |
| 52-week high | $0.0981 |
| 52-week low | $0.0781 |
| Median price | $0.1020 |
| Average price | $0.1248 |
| Largest weekly change | +27.5% (Aug 21, 2024) |
| Weeks tracked | 535 |
| Tracking since | Jul 6, 2016 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Major Pharmaceuticals manufacturer profile
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Drug market
ondansetron hydrochloride market comparison
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Therapeutic class
Serotonin-3 Receptor Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ONDANSETRON HCL 8 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ONDANSETRON HCL 8 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0781 per EA (NDC 00904655261), effective Sep 30, 2026.
How has the price of ONDANSETRON HCL 8 MG TABLET changed over time?
Over the history we have for it, the NADAC for ONDANSETRON HCL 8 MG TABLET has declined 69.4%. It has been tracked across 535 weekly CMS publications since Jul 6, 2016.
What are the highest and lowest recorded NADAC prices for ONDANSETRON HCL 8 MG TABLET?
Since Jul 6, 2016, the NADAC for ONDANSETRON HCL 8 MG TABLET has ranged from a low of $0.0715 (Nov 20, 2024) to a high of $0.2814 (Sep 14, 2016), with a median of $0.1020 per EA.
Are there cheaper alternatives to ONDANSETRON HCL 8 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ONDANSETRON HCL 8 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures ONDANSETRON HCL 8 MG TABLET?
ONDANSETRON HCL 8 MG TABLET (NDC 00904655261) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.