Product Information
MIDODRINE HCL 5 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.1134 per EA under NDC 00904681861. Its NADAC has been published 366 times since Aug 21, 2019.
FDA first approved this application on Sep 12, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The Low Outlier badge above means this manufacturer's average price in the Midodrine Hydrochloride market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
5 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904681861
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
MIDODRINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA077746FDA Approved
9/12/2006
TE Code
AB
On Market Since
9/12/2006
Pharmacological Classes
Price Statistics
The NADAC for MIDODRINE HCL 5 MG TABLET has been published 366 times since Aug 21, 2019, and over the history we have for it it has declined 72.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1134 per EA |
|---|---|
| All-time high | $0.4608 (Dec 11, 2019) |
| All-time low | $0.1084 (Feb 18, 2026) |
| 52-week high | $0.1296 |
| 52-week low | $0.1084 |
| Median price | $0.2336 |
| Average price | $0.2447 |
| Largest weekly change | +38.5% (Aug 21, 2024) |
| Weeks tracked | 366 |
| Tracking since | Aug 21, 2019 |
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MIDODRINE HCL 5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for MIDODRINE HCL 5 MG TABLET, manufactured by Major Pharmaceuticals, is $0.1134 per EA (NDC 00904681861), effective Aug 19, 2026.
How has the price of MIDODRINE HCL 5 MG TABLET changed over time?
Over the history we have for it, the NADAC for MIDODRINE HCL 5 MG TABLET has declined 72.9%. It has been tracked across 366 weekly CMS publications since Aug 21, 2019.
What are the highest and lowest recorded NADAC prices for MIDODRINE HCL 5 MG TABLET?
Since Aug 21, 2019, the NADAC for MIDODRINE HCL 5 MG TABLET has ranged from a low of $0.1084 (Feb 18, 2026) to a high of $0.4608 (Dec 11, 2019), with a median of $0.2336 per EA.
Are there cheaper alternatives to MIDODRINE HCL 5 MG TABLET?
12 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MIDODRINE HCL 5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures MIDODRINE HCL 5 MG TABLET?
MIDODRINE HCL 5 MG TABLET (NDC 00904681861) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.