Product Information
DOXEPIN 25 MG CAPSULE is a generic product labeled by Major Pharmaceuticals, priced at $0.1415 per EA under NDC 00904705361. Its NADAC has been published 289 times since Mar 24, 2021.
FDA first approved this application on Jun 28, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904705361
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DOXEPIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA207482FDA Approved
6/28/2017
TE Code
AB
On Market Since
6/28/2017
Pharmacological Classes
Price Statistics
The NADAC for DOXEPIN 25 MG CAPSULE has been published 289 times since Mar 24, 2021, and over the history we have for it it has declined 52.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1415 per EA |
|---|---|
| All-time high | $0.3458 (Nov 10, 2021) |
| All-time low | $0.1216 (Nov 20, 2024) |
| 52-week high | $0.1415 |
| 52-week low | $0.1242 |
| Median price | $0.1692 |
| Average price | $0.1963 |
| Largest weekly change | +49.1% (Feb 22, 2023) |
| Weeks tracked | 289 |
| Tracking since | Mar 24, 2021 |
Generic Alternatives
The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Major Pharmaceuticals manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Doxepin Hydrochloride market comparison
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Therapeutic class
Tricyclic Antidepressant class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DOXEPIN 25 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for DOXEPIN 25 MG CAPSULE, manufactured by Major Pharmaceuticals, is $0.1415 per EA (NDC 00904705361), effective Sep 30, 2026.
How has the price of DOXEPIN 25 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for DOXEPIN 25 MG CAPSULE has declined 52.1%. It has been tracked across 289 weekly CMS publications since Mar 24, 2021.
What are the highest and lowest recorded NADAC prices for DOXEPIN 25 MG CAPSULE?
Since Mar 24, 2021, the NADAC for DOXEPIN 25 MG CAPSULE has ranged from a low of $0.1216 (Nov 20, 2024) to a high of $0.3458 (Nov 10, 2021), with a median of $0.1692 per EA.
Are there cheaper alternatives to DOXEPIN 25 MG CAPSULE?
Yes. 8 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DOXEPIN 25 MG CAPSULE, is $0.1368 per EA — about 3% below DOXEPIN 25 MG CAPSULE.
Who manufactures DOXEPIN 25 MG CAPSULE?
DOXEPIN 25 MG CAPSULE (NDC 00904705361) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.