Product Information
OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.2360 per EA under NDC 00904709561. Its NADAC has been published 257 times since Sep 22, 2021.
FDA first approved this application on Mar 21, 2018. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 10 mg/1; mg/1
Manufacturer
Major PharmaceuticalsNDC
00904709561
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACETAMINOPHEN; OXYCODONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA207510FDA Approved
3/21/2018
TE Code
AA
On Market Since
6/1/2019
Pharmacological Classes
Price Statistics
The NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET has been published 257 times since Sep 22, 2021, and over the history we have for it it has risen 49.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2360 per EA |
|---|---|
| All-time high | $0.2826 (Jun 11, 2025) |
| All-time low | $0.1580 (Sep 22, 2021) |
| 52-week high | $0.2515 |
| 52-week low | $0.2292 |
| Median price | $0.2116 |
| Average price | $0.2153 |
| Largest weekly change | -22.1% (Nov 20, 2024) |
| Weeks tracked | 257 |
| Tracking since | Sep 22, 2021 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET, manufactured by Major Pharmaceuticals, is $0.2360 per EA (NDC 00904709561), effective Aug 19, 2026.
How has the price of OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET changed over time?
Over the history we have for it, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET has risen 49.4%. It has been tracked across 257 weekly CMS publications since Sep 22, 2021.
What are the highest and lowest recorded NADAC prices for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?
Since Sep 22, 2021, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET has ranged from a low of $0.1580 (Sep 22, 2021) to a high of $0.2826 (Jun 11, 2025), with a median of $0.2116 per EA.
Are there cheaper alternatives to OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?
OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET (NDC 00904709561) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.