Product Information

SIROLIMUS 1 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.8350 per EA under NDC 00904724804. Its NADAC has been published 204 times since Sep 28, 2022.

FDA first approved this application on Mar 12, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SIROLIMUS 1 MG TABLET

Sirolimus
$0.8350per EA

Strength

1 mg/1

NDC

00904724804

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SIROLIMUS

Approval Type

Generic (ANDA)

FDA Application

ANDA214753

FDA Approved

3/12/2021

TE Code

AB

On Market Since

3/13/2021

Pharmacological Classes

Decreased Immunologic Activity
Kinase Inhibitor
Protein Kinase Inhibitors
mTOR Inhibitor Immunosuppressant
mTOR Inhibitors

Price Statistics

The NADAC for SIROLIMUS 1 MG TABLET has been published 204 times since Sep 28, 2022, and over the history we have for it it has declined 77.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.8350 per EA
All-time high$4.6571 (Nov 16, 2022)
All-time low$0.8350 (Aug 19, 2026)
52-week high$1.6054
52-week low$0.8350
Median price$2.0905
Average price$2.3500
Largest weekly change-38.5% (Nov 20, 2024)
Weeks tracked204
Tracking sinceSep 28, 2022

Price History

1W

-4.6%

1M

-12.3%

3M

-17.1%

6M

-41.8%

1Y

-53.3%

3Y

-65.3%

5Y

N/A

All

-77.5%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SIROLIMUS 1 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SIROLIMUS 1 MG TABLET, manufactured by Major Pharmaceuticals, is $0.8350 per EA (NDC 00904724804), effective Aug 19, 2026.

How has the price of SIROLIMUS 1 MG TABLET changed over time?

Over the history we have for it, the NADAC for SIROLIMUS 1 MG TABLET has declined 77.5%. It has been tracked across 204 weekly CMS publications since Sep 28, 2022.

What are the highest and lowest recorded NADAC prices for SIROLIMUS 1 MG TABLET?

Since Sep 28, 2022, the NADAC for SIROLIMUS 1 MG TABLET has ranged from a low of $0.8350 (Aug 19, 2026) to a high of $4.6571 (Nov 16, 2022), with a median of $2.0905 per EA.

Are there cheaper alternatives to SIROLIMUS 1 MG TABLET?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SIROLIMUS 1 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures SIROLIMUS 1 MG TABLET?

SIROLIMUS 1 MG TABLET (NDC 00904724804) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.