Product Information
SIROLIMUS 1 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.7230 per EA under NDC 00904724804. Its NADAC has been published 210 times since Sep 28, 2022.
FDA first approved this application on Mar 12, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904724804
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
SIROLIMUSApproval Type
Generic (ANDA)
FDA Application
ANDA214753FDA Approved
3/12/2021
TE Code
AB
On Market Since
3/13/2021
Pharmacological Classes
Price Statistics
The NADAC for SIROLIMUS 1 MG TABLET has been published 210 times since Sep 28, 2022, and over the history we have for it it has declined 80.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7230 per EA |
|---|---|
| All-time high | $4.6571 (Nov 16, 2022) |
| All-time low | $0.7230 (Sep 23, 2026) |
| 52-week high | $1.4779 |
| 52-week low | $0.7230 |
| Median price | $2.0873 |
| Average price | $2.3057 |
| Largest weekly change | -38.5% (Nov 20, 2024) |
| Weeks tracked | 210 |
| Tracking since | Sep 28, 2022 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Major Pharmaceuticals manufacturer profile
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Drug market
Sirolimus market comparison
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Therapeutic class
Kinase Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of SIROLIMUS 1 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SIROLIMUS 1 MG TABLET, manufactured by Major Pharmaceuticals, is $0.7230 per EA (NDC 00904724804), effective Sep 30, 2026.
How has the price of SIROLIMUS 1 MG TABLET changed over time?
Over the history we have for it, the NADAC for SIROLIMUS 1 MG TABLET has declined 80.5%. It has been tracked across 210 weekly CMS publications since Sep 28, 2022.
What are the highest and lowest recorded NADAC prices for SIROLIMUS 1 MG TABLET?
Since Sep 28, 2022, the NADAC for SIROLIMUS 1 MG TABLET has ranged from a low of $0.7230 (Sep 23, 2026) to a high of $4.6571 (Nov 16, 2022), with a median of $2.0873 per EA.
Are there cheaper alternatives to SIROLIMUS 1 MG TABLET?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SIROLIMUS 1 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures SIROLIMUS 1 MG TABLET?
SIROLIMUS 1 MG TABLET (NDC 00904724804) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.