Product Information
ACETAMINOPHEN ER 650 MG CAPLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0631 per EA under NDC 00904731460. Its NADAC has been published 176 times since May 24, 2023.
FDA first approved this application on Apr 16, 2019.
Strength
650 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904731460
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ACETAMINOPHENApproval Type
Generic (ANDA)
FDA Application
ANDA211544FDA Approved
4/16/2019
On Market Since
3/3/2023
Price Statistics
The NADAC for ACETAMINOPHEN ER 650 MG CAPLET has been published 176 times since May 24, 2023, and over the history we have for it it has declined 13.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0631 per EA |
|---|---|
| All-time high | $0.0729 (Jun 14, 2023) |
| All-time low | $0.0610 (May 22, 2024) |
| 52-week high | $0.0686 |
| 52-week low | $0.0629 |
| Median price | $0.0685 |
| Average price | $0.0675 |
| Largest weekly change | +12.5% (Aug 21, 2024) |
| Weeks tracked | 176 |
| Tracking since | May 24, 2023 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Major Pharmaceuticals manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Acetaminophen market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ACETAMINOPHEN ER 650 MG CAPLET?
The current National Average Drug Acquisition Cost (NADAC) for ACETAMINOPHEN ER 650 MG CAPLET, manufactured by Major Pharmaceuticals, is $0.0631 per EA (NDC 00904731460), effective Sep 30, 2026.
How has the price of ACETAMINOPHEN ER 650 MG CAPLET changed over time?
Over the history we have for it, the NADAC for ACETAMINOPHEN ER 650 MG CAPLET has declined 13.5%. It has been tracked across 176 weekly CMS publications since May 24, 2023.
What are the highest and lowest recorded NADAC prices for ACETAMINOPHEN ER 650 MG CAPLET?
Since May 24, 2023, the NADAC for ACETAMINOPHEN ER 650 MG CAPLET has ranged from a low of $0.0610 (May 22, 2024) to a high of $0.0729 (Jun 14, 2023), with a median of $0.0685 per EA.
Are there cheaper alternatives to ACETAMINOPHEN ER 650 MG CAPLET?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ARTHRITIS PAIN ER 650 MG CAPLT, is $0.0599 per EA — about 5% below ACETAMINOPHEN ER 650 MG CAPLET.
Who manufactures ACETAMINOPHEN ER 650 MG CAPLET?
ACETAMINOPHEN ER 650 MG CAPLET (NDC 00904731460) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.