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Product Information

NASAL DECONGESTANT 0.05% SPRAY is a generic product labeled by Major Pharmaceuticals, priced at $0.1218 per ML under NDC 00904743535. Its NADAC has been published 104 times since Aug 28, 2024.

NASAL DECONGESTANT 0.05% SPRAY

Oxymetazoline hydrochloride
$0.1218per ML
OTC

Strength

.5 mg/mL

NDC

00904743535

Classification

Generic

Dosage Form

SPRAY

Route

NASAL

Effective Date

8/19/2026

Active Ingredients

OXYMETAZOLINE HYDROCHLORIDE

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

12/31/2023

Pharmacological Classes

Imidazolines
Increased Sympathetic Activity
Vasoconstriction
Vasoconstrictor

Price Statistics

The NADAC for NASAL DECONGESTANT 0.05% SPRAY has been published 104 times since Aug 28, 2024, and over the history we have for it it has declined 7.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1218 per ML
All-time high$0.1316 (Nov 13, 2024)
All-time low$0.1202 (Jul 22, 2026)
52-week high$0.1262
52-week low$0.1202
Median price$0.1250
Average price$0.1258
Largest weekly change-2.3% (Jul 23, 2025)
Weeks tracked104
Tracking sinceAug 28, 2024

Price History

1W

+1.4%

1M

+1.4%

3M

-0.4%

6M

-2.0%

1Y

-0.3%

3Y

N/A

5Y

N/A

All

-7.4%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 38% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 38%

1 alternative • Same active ingredient

NASAL DECONGESTANT 0.05% SPRAY
Generic
00904742730•Major Pharmaceuticals
$0.0757
Save 38%

Related Drugs

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$0.0625
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51672203005•Taro Pharmaceuticals U.S.A. Inc.
$0.0625
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NASAL DECONGESTANT 0.05% SPRAY
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$0.0678
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PHENTERMINE 37.5 MG TABLET
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$0.0697
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10702002501•KVK-Tech Inc.
$0.0708
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PHENTERMINE 37.5 MG TABLET
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10702002510•KVK-Tech Inc.
$0.0708
per EA
PHENTERMINE 37.5 MG TABLET
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11534016001•Sunrise Pharmaceutical Inc.
$0.0708
per EA
PHENTERMINE 37.5 MG TABLET
Generic
11534016003•Sunrise Pharmaceutical Inc.
$0.0708
per EA
PHENTERMINE 37.5 MG TABLET
Generic
11534016030•Sunrise Pharmaceutical Inc.
$0.0708
per EA

Frequently asked questions

What is the NADAC price of NASAL DECONGESTANT 0.05% SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for NASAL DECONGESTANT 0.05% SPRAY, manufactured by Major Pharmaceuticals, is $0.1218 per ML (NDC 00904743535), effective Aug 19, 2026.

How has the price of NASAL DECONGESTANT 0.05% SPRAY changed over time?

Over the history we have for it, the NADAC for NASAL DECONGESTANT 0.05% SPRAY has declined 7.4%. It has been tracked across 104 weekly CMS publications since Aug 28, 2024.

What are the highest and lowest recorded NADAC prices for NASAL DECONGESTANT 0.05% SPRAY?

Since Aug 28, 2024, the NADAC for NASAL DECONGESTANT 0.05% SPRAY has ranged from a low of $0.1202 (Jul 22, 2026) to a high of $0.1316 (Nov 13, 2024), with a median of $0.1250 per ML.

Are there cheaper alternatives to NASAL DECONGESTANT 0.05% SPRAY?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, NASAL DECONGESTANT 0.05% SPRAY, is $0.0757 per ML — about 38% below NASAL DECONGESTANT 0.05% SPRAY.

Who manufactures NASAL DECONGESTANT 0.05% SPRAY?

NASAL DECONGESTANT 0.05% SPRAY (NDC 00904743535) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.