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Product Information

8HR ARTHRITIS PAIN ER 650 MG is a generic product labeled by Major Pharmaceuticals, priced at $0.0631 per EA under NDC 00904756160. Its NADAC has been published 44 times since Oct 22, 2025.

FDA first approved this application on Aug 25, 2021.

8HR ARTHRITIS PAIN ER 650 MG

Acetaminophen
$0.0631per EA
OTC

Strength

650 mg/1

NDC

00904756160

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ACETAMINOPHEN

Approval Type

Generic (ANDA)

FDA Application

ANDA215486

FDA Approved

8/25/2021

On Market Since

5/6/2025

Price Statistics

The NADAC for 8HR ARTHRITIS PAIN ER 650 MG has been published 44 times since Oct 22, 2025, and over the history we have for it it has declined 7.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0631 per EA
All-time high$0.0686 (Jan 14, 2026)
All-time low$0.0629 (Jul 22, 2026)
52-week high$0.0686
52-week low$0.0629
Median price$0.0661
Average price$0.0660
Largest weekly change-2.5% (Apr 22, 2026)
Weeks tracked44
Tracking sinceOct 22, 2025

Price History

1W

+0.3%

1M

+0.1%

3M

-0.9%

6M

-6.2%

1Y

N/A

3Y

N/A

5Y

N/A

All

-7.1%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 5%

7 alternatives • Same active ingredient

QC ARTHRITIS PAIN ER 650 MG
Generic
63868008901•Chain Drug Marketing Association
$0.0599
Save 5%
ACETAMINOPHEN ER 650 MG TABLET
Generic
68001049500•BluePoint Laboratories
$0.0631
8HR ARTHRITIS PAIN ER 650 MG
Generic
70000073301•Cardinal Health
$0.0631
GNP 8HR ARTHRIT PAIN ER 650 MG
Generic
46122062971•AmerisourceBergen
$0.0631
GS ARTHRITIS PAIN ER 650 MG
Generic
00113054478•L. Perrigo Company
$0.0631
ACETAMINOPHEN ER 650 MG CAPLET
Generic
00904731460•Major Pharmaceuticals
$0.0631
FT 8 HOUR PAIN RLF ER 650 MG
Generic
70677112301•Strategic Sourcing Services LLC
$0.0631

Related Drugs

Same classification

No related drugs found.

Frequently asked questions

What is the NADAC price of 8HR ARTHRITIS PAIN ER 650 MG?

The current National Average Drug Acquisition Cost (NADAC) for 8HR ARTHRITIS PAIN ER 650 MG, manufactured by Major Pharmaceuticals, is $0.0631 per EA (NDC 00904756160), effective Aug 19, 2026.

How has the price of 8HR ARTHRITIS PAIN ER 650 MG changed over time?

Over the history we have for it, the NADAC for 8HR ARTHRITIS PAIN ER 650 MG has declined 7.1%. It has been tracked across 44 weekly CMS publications since Oct 22, 2025.

What are the highest and lowest recorded NADAC prices for 8HR ARTHRITIS PAIN ER 650 MG?

Since Oct 22, 2025, the NADAC for 8HR ARTHRITIS PAIN ER 650 MG has ranged from a low of $0.0629 (Jul 22, 2026) to a high of $0.0686 (Jan 14, 2026), with a median of $0.0661 per EA.

Are there cheaper alternatives to 8HR ARTHRITIS PAIN ER 650 MG?

Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, QC ARTHRITIS PAIN ER 650 MG, is $0.0599 per EA — about 5% below 8HR ARTHRITIS PAIN ER 650 MG.

Who manufactures 8HR ARTHRITIS PAIN ER 650 MG?

8HR ARTHRITIS PAIN ER 650 MG (NDC 00904756160) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.