Product Information

TOPIRAMATE ER 25 MG CAPSULE is a generic product labeled by Endo USA Inc., priced at $4.1399 per EA under NDC 10370036501. Its NADAC has been published 163 times since Aug 23, 2023.

FDA first approved this application on Mar 1, 2023. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

TOPIRAMATE ER 25 MG CAPSULE

Topiramate
$4.1399per EA

Strength

25 mg/1

Manufacturer

Endo USA Inc.

NDC

10370036501

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

9/23/2026

Active Ingredients

TOPIRAMATE

Approval Type

Generic (ANDA)

FDA Application

ANDA205976

FDA Approved

3/1/2023

TE Code

AB1

On Market Since

5/24/2023

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Cytochrome P450 3A4 Inducers
Decreased Central Nervous System Disorganized Electrical Activity

Price Statistics

The NADAC for TOPIRAMATE ER 25 MG CAPSULE has been published 163 times since Aug 23, 2023, and over the history we have for it it has declined 55.6%. The table below summarizes its recorded NADAC range and movement.

Current price$4.1399 per EA
All-time high$9.3295 (Oct 11, 2023)
All-time low$2.8599 (Nov 20, 2024)
52-week high$4.4141
52-week low$3.7241
Median price$4.7607
Average price$5.2826
Largest weekly change-46.2% (Nov 20, 2024)
Weeks tracked163
Tracking sinceAug 23, 2023

Price History

1W

0.0%

1M

-1.6%

3M

+8.1%

6M

+11.2%

1Y

-5.9%

3Y

-55.6%

5Y

N/A

All

-55.6%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 94% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of TOPIRAMATE ER 25 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE ER 25 MG CAPSULE, manufactured by Endo USA Inc., is $4.1399 per EA (NDC 10370036501), effective Sep 30, 2026.

How has the price of TOPIRAMATE ER 25 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for TOPIRAMATE ER 25 MG CAPSULE has declined 55.6%. It has been tracked across 163 weekly CMS publications since Aug 23, 2023.

What are the highest and lowest recorded NADAC prices for TOPIRAMATE ER 25 MG CAPSULE?

Since Aug 23, 2023, the NADAC for TOPIRAMATE ER 25 MG CAPSULE has ranged from a low of $2.8599 (Nov 20, 2024) to a high of $9.3295 (Oct 11, 2023), with a median of $4.7607 per EA.

Are there cheaper alternatives to TOPIRAMATE ER 25 MG CAPSULE?

Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TOPIRAMATE 25 MG SPRINKLE CAP, is $0.2459 per EA — about 94% below TOPIRAMATE ER 25 MG CAPSULE.

Who manufactures TOPIRAMATE ER 25 MG CAPSULE?

TOPIRAMATE ER 25 MG CAPSULE (NDC 10370036501) is labeled by Endo USA Inc., and CMS classifies it as a generic product.