Product Information
TOPIRAMATE ER 25 MG SPRINKL CAP is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $2.2543 per EA under NDC 70710103903. Its NADAC has been published 182 times since Apr 12, 2023.
FDA first approved this application on Nov 29, 2022. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
70710103903
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
TOPIRAMATEApproval Type
Generic (ANDA)
FDA Application
ANDA208949FDA Approved
11/29/2022
TE Code
AB2
On Market Since
1/17/2023
Pharmacological Classes
Price Statistics
The NADAC for TOPIRAMATE ER 25 MG SPRINKL CAP has been published 182 times since Apr 12, 2023, and over the history we have for it it has declined 47.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.2543 per EA |
|---|---|
| All-time high | $5.1912 (Apr 10, 2024) |
| All-time low | $2.2543 (Sep 23, 2026) |
| 52-week high | $3.7915 |
| 52-week low | $2.2543 |
| Median price | $3.8178 |
| Average price | $3.9093 |
| Largest weekly change | +19.9% (Jul 19, 2023) |
| Weeks tracked | 182 |
| Tracking since | Apr 12, 2023 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 89% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Zydus Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
Topiramate market comparison
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of TOPIRAMATE ER 25 MG SPRINKL CAP?
The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE ER 25 MG SPRINKL CAP, manufactured by Zydus Pharmaceuticals (USA) Inc., is $2.2543 per EA (NDC 70710103903), effective Sep 30, 2026.
How has the price of TOPIRAMATE ER 25 MG SPRINKL CAP changed over time?
Over the history we have for it, the NADAC for TOPIRAMATE ER 25 MG SPRINKL CAP has declined 47.4%. It has been tracked across 182 weekly CMS publications since Apr 12, 2023.
What are the highest and lowest recorded NADAC prices for TOPIRAMATE ER 25 MG SPRINKL CAP?
Since Apr 12, 2023, the NADAC for TOPIRAMATE ER 25 MG SPRINKL CAP has ranged from a low of $2.2543 (Sep 23, 2026) to a high of $5.1912 (Apr 10, 2024), with a median of $3.8178 per EA.
Are there cheaper alternatives to TOPIRAMATE ER 25 MG SPRINKL CAP?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TOPIRAMATE 25 MG SPRINKLE CAP, is $0.2459 per EA — about 89% below TOPIRAMATE ER 25 MG SPRINKL CAP.
Who manufactures TOPIRAMATE ER 25 MG SPRINKL CAP?
TOPIRAMATE ER 25 MG SPRINKL CAP (NDC 70710103903) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.