Product Information

TOPIRAMATE ER 25 MG SPRINKL CAP is a generic product labeled by Vitruvias Therapeutics Inc., priced at $2.3344 per EA under NDC 69680017730. Its NADAC has been published 59 times since Jul 9, 2025.

FDA first approved this application on Nov 5, 2024. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

TOPIRAMATE ER 25 MG SPRINKL CAP

Topiramate
$2.3344per EA

Strength

25 mg/1

NDC

69680017730

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

TOPIRAMATE

Approval Type

Generic (ANDA)

FDA Application

ANDA215638

FDA Approved

11/5/2024

TE Code

AB2

On Market Since

4/7/2025

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Cytochrome P450 3A4 Inducers
Decreased Central Nervous System Disorganized Electrical Activity

Price Statistics

The NADAC for TOPIRAMATE ER 25 MG SPRINKL CAP has been published 59 times since Jul 9, 2025, and over the history we have for it it has declined 37.2%. The table below summarizes its recorded NADAC range and movement.

Current price$2.3344 per EA
All-time high$3.8264 (Sep 10, 2025)
All-time low$2.3344 (Aug 19, 2026)
52-week high$3.8264
52-week low$2.3344
Median price$3.6455
Average price$3.3880
Largest weekly change-9.3% (May 20, 2026)
Weeks tracked59
Tracking sinceJul 9, 2025

Price History

1W

-5.6%

1M

-5.6%

3M

-17.4%

6M

-34.7%

1Y

-39.0%

3Y

N/A

5Y

N/A

All

-37.2%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 89% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of TOPIRAMATE ER 25 MG SPRINKL CAP?

The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE ER 25 MG SPRINKL CAP, manufactured by Vitruvias Therapeutics Inc., is $2.3344 per EA (NDC 69680017730), effective Aug 19, 2026.

How has the price of TOPIRAMATE ER 25 MG SPRINKL CAP changed over time?

Over the history we have for it, the NADAC for TOPIRAMATE ER 25 MG SPRINKL CAP has declined 37.2%. It has been tracked across 59 weekly CMS publications since Jul 9, 2025.

What are the highest and lowest recorded NADAC prices for TOPIRAMATE ER 25 MG SPRINKL CAP?

Since Jul 9, 2025, the NADAC for TOPIRAMATE ER 25 MG SPRINKL CAP has ranged from a low of $2.3344 (Aug 19, 2026) to a high of $3.8264 (Sep 10, 2025), with a median of $3.6455 per EA.

Are there cheaper alternatives to TOPIRAMATE ER 25 MG SPRINKL CAP?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TOPIRAMATE 25 MG SPRINKLE CAP, is $0.2547 per EA — about 89% below TOPIRAMATE ER 25 MG SPRINKL CAP.

Who manufactures TOPIRAMATE ER 25 MG SPRINKL CAP?

TOPIRAMATE ER 25 MG SPRINKL CAP (NDC 69680017730) is labeled by Vitruvias Therapeutics Inc., and CMS classifies it as a generic product.