Product Information
TOPIRAMATE 25 MG SPRINKLE CAP is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $0.2547 per EA under NDC 24979021104. Its NADAC has been published 129 times since Mar 6, 2024.
FDA first approved this application on Dec 5, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Upsher-Smith Laboratories LLCNDC
24979021104
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
TOPIRAMATEApproval Type
Generic (ANDA)
FDA Application
ANDA217694FDA Approved
12/5/2023
TE Code
AB
On Market Since
12/5/2023
Pharmacological Classes
Price Statistics
The NADAC for TOPIRAMATE 25 MG SPRINKLE CAP has been published 129 times since Mar 6, 2024, and over the history we have for it it has declined 57.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2547 per EA |
|---|---|
| All-time high | $0.7880 (Jun 12, 2024) |
| All-time low | $0.2547 (Aug 19, 2026) |
| 52-week high | $0.4019 |
| 52-week low | $0.2547 |
| Median price | $0.4054 |
| Average price | $0.4580 |
| Largest weekly change | -25.0% (Nov 20, 2024) |
| Weeks tracked | 129 |
| Tracking since | Mar 6, 2024 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TOPIRAMATE 25 MG SPRINKLE CAP?
The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE 25 MG SPRINKLE CAP, manufactured by Upsher-Smith Laboratories LLC, is $0.2547 per EA (NDC 24979021104), effective Aug 19, 2026.
How has the price of TOPIRAMATE 25 MG SPRINKLE CAP changed over time?
Over the history we have for it, the NADAC for TOPIRAMATE 25 MG SPRINKLE CAP has declined 57.9%. It has been tracked across 129 weekly CMS publications since Mar 6, 2024.
What are the highest and lowest recorded NADAC prices for TOPIRAMATE 25 MG SPRINKLE CAP?
Since Mar 6, 2024, the NADAC for TOPIRAMATE 25 MG SPRINKLE CAP has ranged from a low of $0.2547 (Aug 19, 2026) to a high of $0.7880 (Jun 12, 2024), with a median of $0.4054 per EA.
Are there cheaper alternatives to TOPIRAMATE 25 MG SPRINKLE CAP?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TOPIRAMATE 25 MG SPRINKLE CAP in a comparable dosage form, but none are currently priced below it.
Who manufactures TOPIRAMATE 25 MG SPRINKLE CAP?
TOPIRAMATE 25 MG SPRINKLE CAP (NDC 24979021104) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.