Product Information
ESTRADIOL 0.1% (0.5 MG) GEL PKT is a generic product labeled by Trigen Laboratories, LLC, priced at $1.3243 per EA under NDC 13811009132. Its NADAC has been published 158 times since Jun 21, 2023.
Strength
.5 mg/.5g
Manufacturer
Trigen Laboratories, LLCNDC
13811009132
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA022038On Market Since
10/10/2022
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has been published 158 times since Jun 21, 2023, and over the history we have for it it has declined 63.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3243 per EA |
|---|---|
| All-time high | $3.9353 (Sep 13, 2023) |
| All-time low | $1.1300 (Nov 20, 2024) |
| 52-week high | $2.1810 |
| 52-week low | $1.3243 |
| Median price | $2.0017 |
| Average price | $2.2963 |
| Largest weekly change | -47.1% (Apr 17, 2024) |
| Weeks tracked | 158 |
| Tracking since | Jun 21, 2023 |
Generic Alternatives
The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 96% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.1% (0.5 MG) GEL PKT?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (0.5 MG) GEL PKT, manufactured by Trigen Laboratories, LLC, is $1.3243 per EA (NDC 13811009132), effective Jun 24, 2026.
How has the price of ESTRADIOL 0.1% (0.5 MG) GEL PKT changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has declined 63.1%. It has been tracked across 158 weekly CMS publications since Jun 21, 2023.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (0.5 MG) GEL PKT?
Since Jun 21, 2023, the NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has ranged from a low of $1.1300 (Nov 20, 2024) to a high of $3.9353 (Sep 13, 2023), with a median of $2.0017 per EA.
Are there cheaper alternatives to ESTRADIOL 0.1% (0.5 MG) GEL PKT?
Yes. 4 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, ESTRADIOL 0.5 MG TABLET, is $0.0592 per EA — about 96% below ESTRADIOL 0.1% (0.5 MG) GEL PKT.
Who manufactures ESTRADIOL 0.1% (0.5 MG) GEL PKT?
ESTRADIOL 0.1% (0.5 MG) GEL PKT (NDC 13811009132) is labeled by Trigen Laboratories, LLC, and CMS classifies it as a generic product.
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