Product Information
EPLERENONE 25 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.3052 per EA under NDC 16571017303. Its NADAC has been published 76 times since Mar 12, 2025.
FDA first approved this application on Mar 23, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Rising Pharma Holdings Inc.NDC
16571017303
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
EPLERENONEApproval Type
Generic (ANDA)
FDA Application
ANDA214663FDA Approved
3/23/2022
TE Code
AB
On Market Since
9/30/2024
Pharmacological Classes
Price Statistics
The NADAC for EPLERENONE 25 MG TABLET has been published 76 times since Mar 12, 2025, and over the history we have for it it has declined 34.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3052 per EA |
|---|---|
| All-time high | $0.5027 (Jul 16, 2025) |
| All-time low | $0.3001 (Jul 22, 2026) |
| 52-week high | $0.4950 |
| 52-week low | $0.3001 |
| Median price | $0.3825 |
| Average price | $0.4009 |
| Largest weekly change | -10.7% (Nov 19, 2025) |
| Weeks tracked | 76 |
| Tracking since | Mar 12, 2025 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of EPLERENONE 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for EPLERENONE 25 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.3052 per EA (NDC 16571017303), effective Aug 19, 2026.
How has the price of EPLERENONE 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for EPLERENONE 25 MG TABLET has declined 34.1%. It has been tracked across 76 weekly CMS publications since Mar 12, 2025.
What are the highest and lowest recorded NADAC prices for EPLERENONE 25 MG TABLET?
Since Mar 12, 2025, the NADAC for EPLERENONE 25 MG TABLET has ranged from a low of $0.3001 (Jul 22, 2026) to a high of $0.5027 (Jul 16, 2025), with a median of $0.3825 per EA.
Are there cheaper alternatives to EPLERENONE 25 MG TABLET?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as EPLERENONE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures EPLERENONE 25 MG TABLET?
EPLERENONE 25 MG TABLET (NDC 16571017303) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.