Eplerenone
30 NDCs across 8 manufacturers|29 Generic,1 Brand
Eplerenone is used to treat systolic heart failure and hypertension, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Sep 27, 2002, and the first generic was approved Jul 30, 2008. FDA's Orange Book lists 18 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $28 million on Eplerenone across 321,000 claims for 83,000 beneficiaries.
Eplerenone is available as 30 NDCs from 8 manufacturers (29 generic, 1 brand), with NADAC prices from $0.31 to $14.11 per EA — the most expensive product costs about 46× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
30
29G / 1B
Manufacturers
8
competing in market
Price Spread
$0.31 – $14.11
per EA
7d Activity
avg -1.1% WoW · of 30 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Mylan Pharmaceuticals Inc. manufacturer profile
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Lead class
Aldosterone Antagonist class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
8 manufacturers producing EPLERENONE(2 pricing outliers)
Frequently Asked Questions
What is Eplerenone used to treat?
Eplerenone is used to treat systolic heart failure and hypertension, per the National Library of Medicine's MED-RT classification.
When did Eplerenone become available as a generic?
FDA approved the first generic Eplerenone (ANDA) on Jul 30, 2008. The Orange Book currently lists 18 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Eplerenone?
In 2024, Medicare Part D spent $28 million on Eplerenone across 321,000 claims for 83,000 beneficiaries.
How many Eplerenone products are on the market?
The Eplerenone drug market contains 30 NDCs from 8 manufacturers — 29 generic and 1 brand product.
What is the price range for Eplerenone?
NADAC reference prices for Eplerenone range from $0.3052 to $14.1067 per EA — the most expensive product costs about 46× the cheapest.
Is generic Eplerenone cheaper than brand?
The average generic NADAC for Eplerenone is $0.3772 per EA, versus $14.1067 for brand-labeled products — brand versions average about 37× the generic price.
Which manufacturers make Eplerenone?
8 manufacturers list Eplerenone in NADAC. Ranked by number of NDCs, the largest are Mylan Pharmaceuticals Inc. (8), Rising Pharma Holdings Inc. (4), Camber Pharmaceuticals Inc. (4), Accord Healthcare Inc. (4), Westminster Pharmaceuticals LLC (4).
How has the price of Eplerenone changed recently?
Over the past 7 days, 14 Eplerenone NDCs rose and 13 fell, with a market-wide average change of -1.1%.