Product Information

CYCLOBENZAPRINE 5 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.0215 per EA under NDC 16571078250. Its NADAC has been published 244 times since Dec 22, 2021.

FDA first approved this application on Sep 26, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CYCLOBENZAPRINE 5 MG TABLET

Cyclobenzaprine Hydrochloride
$0.0215per EA

Strength

5 mg/1

NDC

16571078250

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA078643

FDA Approved

9/26/2008

TE Code

AB

On Market Since

9/26/2008

Pharmacological Classes

Centrally-mediated Muscle Relaxation
Muscle Relaxant

Price Statistics

The NADAC for CYCLOBENZAPRINE 5 MG TABLET has been published 244 times since Dec 22, 2021, and over the history we have for it it has declined 28.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0215 per EA
All-time high$0.0303 (Feb 16, 2022)
All-time low$0.0157 (Nov 20, 2024)
52-week high$0.0219
52-week low$0.0209
Median price$0.0220
Average price$0.0228
Largest weekly change+36.3% (Aug 21, 2024)
Weeks tracked244
Tracking sinceDec 22, 2021

Price History

1W

+1.6%

1M

+1.6%

3M

+0.6%

6M

+2.4%

1Y

-1.0%

3Y

-4.5%

5Y

N/A

All

-28.8%

Generic Alternatives

The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CYCLOBENZAPRINE 5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for CYCLOBENZAPRINE 5 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.0215 per EA (NDC 16571078250), effective Aug 19, 2026.

How has the price of CYCLOBENZAPRINE 5 MG TABLET changed over time?

Over the history we have for it, the NADAC for CYCLOBENZAPRINE 5 MG TABLET has declined 28.8%. It has been tracked across 244 weekly CMS publications since Dec 22, 2021.

What are the highest and lowest recorded NADAC prices for CYCLOBENZAPRINE 5 MG TABLET?

Since Dec 22, 2021, the NADAC for CYCLOBENZAPRINE 5 MG TABLET has ranged from a low of $0.0157 (Nov 20, 2024) to a high of $0.0303 (Feb 16, 2022), with a median of $0.0220 per EA.

Are there cheaper alternatives to CYCLOBENZAPRINE 5 MG TABLET?

9 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CYCLOBENZAPRINE 5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures CYCLOBENZAPRINE 5 MG TABLET?

CYCLOBENZAPRINE 5 MG TABLET (NDC 16571078250) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.