Product Information
LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB is a generic product labeled by NorthStar Rx LLC, priced at $0.0762 per EA under NDC 16714022403. Its NADAC has been published 83 times since Mar 5, 2025.
FDA first approved this application on Jan 6, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
12.5; 100 mg/1; mg/1
Manufacturer
NorthStar Rx LLCNDC
16714022403
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
HYDROCHLOROTHIAZIDE; LOSARTAN POTASSIUMApproval Type
Generic (ANDA)
FDA Application
ANDA091629FDA Approved
1/6/2010
TE Code
AB
On Market Since
9/4/2024
Pharmacological Classes
Price Statistics
The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB has been published 83 times since Mar 5, 2025, and over the history we have for it it has declined 20.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0762 per EA |
|---|---|
| All-time high | $0.0977 (Apr 16, 2025) |
| All-time low | $0.0742 (Jul 22, 2026) |
| 52-week high | $0.0951 |
| 52-week low | $0.0742 |
| Median price | $0.0812 |
| Average price | $0.0851 |
| Largest weekly change | -7.7% (Nov 19, 2025) |
| Weeks tracked | 83 |
| Tracking since | Mar 5, 2025 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
NorthStar Rx LLC manufacturer profile
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Drug market
Losartan Potassium and Hydrochlorothiazide market comparison
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Therapeutic class
Angiotensin 2 Receptor Blocker class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB, manufactured by NorthStar Rx LLC, is $0.0762 per EA (NDC 16714022403), effective Sep 30, 2026.
How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB changed over time?
Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB has declined 20.6%. It has been tracked across 83 weekly CMS publications since Mar 5, 2025.
What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?
Since Mar 5, 2025, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB has ranged from a low of $0.0742 (Jul 22, 2026) to a high of $0.0977 (Apr 16, 2025), with a median of $0.0812 per EA.
Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?
LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB (NDC 16714022403) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.