Product Information

LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB is a generic product labeled by NorthStar Rx LLC, priced at $0.0573 per EA under NDC 16714022604. Its NADAC has been published 515 times since Nov 28, 2013.

FDA first approved this application on Jan 6, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB

Losartan Potassium and Hydrochlorothiazide
$0.0573per EA

Strength

12.5; 50 mg/1; mg/1

Manufacturer

NorthStar Rx LLC

NDC

16714022604

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA091629

FDA Approved

1/6/2010

TE Code

AB

On Market Since

9/4/2024

Pharmacological Classes

Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Blocker
Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has been published 515 times since Nov 28, 2013, and over the history we have for it it has declined 33.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0573 per EA
All-time high$0.1854 (Apr 15, 2020)
All-time low$0.0573 (Aug 19, 2026)
52-week high$0.0797
52-week low$0.0573
Median price$0.0813
Average price$0.0992
Largest weekly change-49.5% (May 21, 2025)
Weeks tracked515
Tracking sinceNov 28, 2013

Price History

1W

-4.7%

1M

-4.7%

3M

-7.3%

6M

-18.7%

1Y

-28.1%

3Y

-61.7%

5Y

-62.3%

All

-33.9%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB, manufactured by NorthStar Rx LLC, is $0.0573 per EA (NDC 16714022604), effective Aug 19, 2026.

How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB changed over time?

Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has declined 33.9%. It has been tracked across 515 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

Since Nov 28, 2013, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has ranged from a low of $0.0573 (Aug 19, 2026) to a high of $0.1854 (Apr 15, 2020), with a median of $0.0813 per EA.

Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB (NDC 16714022604) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.