Product Information

SERTRALINE HCL 100 MG TABLET is a generic product labeled by NorthStar Rx LLC, priced at $0.0504 per EA under NDC 16714061305. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Feb 6, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SERTRALINE HCL 100 MG TABLET

Sertraline Hydrochloride
$0.0504per EA

Strength

100 mg/1

Manufacturer

NorthStar Rx LLC

NDC

16714061305

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA077206

FDA Approved

2/6/2007

TE Code

AB

On Market Since

2/6/2007

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for SERTRALINE HCL 100 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 14.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0504 per EA
All-time high$0.0790 (Sep 16, 2020)
All-time low$0.0414 (Nov 20, 2024)
52-week high$0.0529
52-week low$0.0496
Median price$0.0566
Average price$0.0574
Largest weekly change-24.3% (Nov 20, 2024)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-0.9%

1M

-0.9%

3M

+1.2%

6M

-2.7%

1Y

-4.7%

3Y

-17.6%

5Y

-16.6%

All

-14.3%

Generic Alternatives

The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SERTRALINE HCL 100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 100 MG TABLET, manufactured by NorthStar Rx LLC, is $0.0504 per EA (NDC 16714061305), effective Aug 19, 2026.

How has the price of SERTRALINE HCL 100 MG TABLET changed over time?

Over the history we have for it, the NADAC for SERTRALINE HCL 100 MG TABLET has declined 14.3%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 100 MG TABLET?

Since Nov 28, 2013, the NADAC for SERTRALINE HCL 100 MG TABLET has ranged from a low of $0.0414 (Nov 20, 2024) to a high of $0.0790 (Sep 16, 2020), with a median of $0.0566 per EA.

Are there cheaper alternatives to SERTRALINE HCL 100 MG TABLET?

8 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SERTRALINE HCL 100 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures SERTRALINE HCL 100 MG TABLET?

SERTRALINE HCL 100 MG TABLET (NDC 16714061305) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.