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Product Information

DAPTOMYCIN 500 MG VIAL is a generic product labeled by NorthStar Rx LLC, priced at $21.8463 per EA under NDC 16714089201. Its NADAC has been published 116 times since Apr 17, 2024.

FDA first approved this application on May 1, 2019. Its Orange Book therapeutic-equivalence code is AP.

DAPTOMYCIN 500 MG VIAL

Daptomycin
$21.8463per EA
Discontinued

Strength

50 mg/mL

Manufacturer

NorthStar Rx LLC

NDC

16714089201

Classification

Generic

Dosage Form

INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION

Route

INTRAVENOUS

Effective Date

6/17/2026

Active Ingredients

DAPTOMYCIN

Approval Type

Generic (ANDA)

FDA Application

ANDA208375

FDA Approved

5/1/2019

TE Code

AP

On Market Since

6/13/2022

Pharmacological Classes

Lipopeptide Antibacterial
Lipopeptides

Price Statistics

The NADAC for DAPTOMYCIN 500 MG VIAL has been published 116 times since Apr 17, 2024, and over the history we have for it it has declined 12.1%. The table below summarizes its recorded NADAC range and movement.

Current price$21.8463 per EA
All-time high$28.3900 (Sep 11, 2024)
All-time low$20.1020 (Oct 22, 2025)
52-week high$24.2743
52-week low$20.1020
Median price$22.0741
Average price$22.8360
Largest weekly change-17.2% (Oct 22, 2025)
Weeks tracked116
Tracking sinceApr 17, 2024

Price History

1W

N/A

1M

N/A

3M

0.0%

6M

+5.2%

1Y

-10.0%

3Y

N/A

5Y

N/A

All

-12.1%

Last surveyed Jul 1, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Daptomycin market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Related Drugs

Same classification

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DAPTOMYCIN 350 MG VIAL
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71288001715•Meitheal Pharmaceuticals Inc.
$13.4180
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DAPTOMYCIN 350 MG VIAL
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71288001791•Meitheal Pharmaceuticals Inc.
$13.4180
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71839010801•BE Pharmaceuticals Inc.
$13.4180
per EA
DAPTOMYCIN 500 MG VIAL
Generic
00409012201•Hospira Inc.
$20.7686
per EA
DAPTOMYCIN 500 MG VIAL
Generic
70594006001•Xellia Pharmaceuticals USA LLC
$20.7686
per EA
DAPTOMYCIN 500 MG VIAL
Generic
25021017415•Sagent Pharmaceuticals
$22.6865
per EA
DAPTOMYCIN 500 MG VIAL
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25021017416•Sagent Pharmaceuticals
$22.6865
per EA
DAPTOMYCIN 500 MG VIAL
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55150034401•Eugia US LLC
$22.6865
per EA

Frequently asked questions

What is the NADAC price of DAPTOMYCIN 500 MG VIAL?

The current National Average Drug Acquisition Cost (NADAC) for DAPTOMYCIN 500 MG VIAL, manufactured by NorthStar Rx LLC, is $21.8463 per EA (NDC 16714089201), effective Jul 1, 2026.

How has the price of DAPTOMYCIN 500 MG VIAL changed over time?

Over the history we have for it, the NADAC for DAPTOMYCIN 500 MG VIAL has declined 12.1%. It has been tracked across 116 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for DAPTOMYCIN 500 MG VIAL?

Since Apr 17, 2024, the NADAC for DAPTOMYCIN 500 MG VIAL has ranged from a low of $20.1020 (Oct 22, 2025) to a high of $28.3900 (Sep 11, 2024), with a median of $22.0741 per EA.

Are there cheaper alternatives to DAPTOMYCIN 500 MG VIAL?

No other NADAC-published product currently shares the active ingredient and strength of DAPTOMYCIN 500 MG VIAL in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures DAPTOMYCIN 500 MG VIAL?

DAPTOMYCIN 500 MG VIAL (NDC 16714089201) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.