Product Information

BUPROPION HCL XL 150 MG TABLET is a generic product labeled by Accord Healthcare Inc., priced at $0.0787 per EA under NDC 16729044310. Its NADAC has been published 402 times since Dec 12, 2018.

FDA first approved this application on Oct 31, 2018. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL XL 150 MG TABLET

BUPROPION HYDROCHLORIDE
$0.0787per EA

Strength

150 mg/1

NDC

16729044310

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA210497

FDA Approved

10/31/2018

TE Code

AB3

On Market Since

11/8/2018

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 150 MG TABLET has been published 402 times since Dec 12, 2018, and over the history we have for it it has declined 71.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0787 per EA
All-time high$0.3117 (Aug 14, 2019)
All-time low$0.0745 (Nov 20, 2024)
52-week high$0.1015
52-week low$0.0770
Median price$0.1168
Average price$0.1446
Largest weekly change-30.3% (Nov 20, 2024)
Weeks tracked402
Tracking sinceDec 12, 2018

Price History

1W

+1.2%

1M

+1.1%

3M

-0.3%

6M

+0.2%

1Y

-22.5%

3Y

-22.1%

5Y

-49.6%

All

-71.9%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 150 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 150 MG TABLET, manufactured by Accord Healthcare Inc., is $0.0787 per EA (NDC 16729044310), effective Aug 19, 2026.

How has the price of BUPROPION HCL XL 150 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 150 MG TABLET has declined 71.9%. It has been tracked across 402 weekly CMS publications since Dec 12, 2018.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 150 MG TABLET?

Since Dec 12, 2018, the NADAC for BUPROPION HCL XL 150 MG TABLET has ranged from a low of $0.0745 (Nov 20, 2024) to a high of $0.3117 (Aug 14, 2019), with a median of $0.1168 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 150 MG TABLET?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL XL 150 MG TABLET, is $0.0770 per EA — about 2% below BUPROPION HCL XL 150 MG TABLET.

Who manufactures BUPROPION HCL XL 150 MG TABLET?

BUPROPION HCL XL 150 MG TABLET (NDC 16729044310) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.