Product Information

BUPROPION HCL SR 100 MG TABLET is a generic product labeled by Solco Healthcare US LLC, priced at $0.0687 per EA under NDC 43547028850. Its NADAC has been published 560 times since Dec 2, 2015.

FDA first approved this application on May 26, 2015. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL SR 100 MG TABLET

Bupropion hydrochloride
$0.0687per EA

Strength

100 mg/1

NDC

43547028850

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA202304

FDA Approved

5/26/2015

TE Code

AB1

On Market Since

11/1/2014

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL SR 100 MG TABLET has been published 560 times since Dec 2, 2015, and over the history we have for it it has declined 65.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0687 per EA
All-time high$0.2290 (Apr 13, 2016)
All-time low$0.0639 (Oct 22, 2025)
52-week high$0.0812
52-week low$0.0639
Median price$0.1439
Average price$0.1388
Largest weekly change+30.2% (Jun 19, 2024)
Weeks tracked560
Tracking sinceDec 2, 2015

Price History

1W

+0.0%

1M

-8.7%

3M

-8.4%

6M

-3.0%

1Y

-25.5%

3Y

-31.3%

5Y

-48.7%

All

-65.9%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL SR 100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 100 MG TABLET, manufactured by Solco Healthcare US LLC, is $0.0687 per EA (NDC 43547028850), effective Aug 19, 2026.

How has the price of BUPROPION HCL SR 100 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL SR 100 MG TABLET has declined 65.9%. It has been tracked across 560 weekly CMS publications since Dec 2, 2015.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 100 MG TABLET?

Since Dec 2, 2015, the NADAC for BUPROPION HCL SR 100 MG TABLET has ranged from a low of $0.0639 (Oct 22, 2025) to a high of $0.2290 (Apr 13, 2016), with a median of $0.1439 per EA.

Are there cheaper alternatives to BUPROPION HCL SR 100 MG TABLET?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL SR 100 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPROPION HCL SR 100 MG TABLET?

BUPROPION HCL SR 100 MG TABLET (NDC 43547028850) is labeled by Solco Healthcare US LLC, and CMS classifies it as a generic product.