Product Information
BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Accord Healthcare Inc., priced at $0.1115 per EA under NDC 16729044410. Its NADAC has been published 376 times since Apr 17, 2019.
Strength
300 mg/1
Manufacturer
Accord Healthcare Inc.NDC
16729044410
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA210497On Market Since
3/25/2019
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 376 times since Apr 17, 2019, and over the history we have for it it has declined 70.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1115 per EA |
|---|---|
| All-time high | $0.4702 (Sep 11, 2019) |
| All-time low | $0.1033 (Feb 18, 2026) |
| 52-week high | $0.1504 |
| 52-week low | $0.1033 |
| Median price | $0.1776 |
| Average price | $0.1960 |
| Largest weekly change | -33.9% (Sep 18, 2019) |
| Weeks tracked | 376 |
| Tracking since | Apr 17, 2019 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Accord Healthcare Inc., is $0.1115 per EA (NDC 16729044410), effective Jun 24, 2026.
How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 70.8%. It has been tracked across 376 weekly CMS publications since Apr 17, 2019.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?
Since Apr 17, 2019, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.4702 (Sep 11, 2019), with a median of $0.1776 per EA.
Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?
Yes. 2 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, BUPROPION HCL XL 300 MG TABLET, is $0.1073 per EA — about 4% below BUPROPION HCL XL 300 MG TABLET.
Who manufactures BUPROPION HCL XL 300 MG TABLET?
BUPROPION HCL XL 300 MG TABLET (NDC 16729044410) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.
Related Drugs
Same classification