Product Information

FLUOROURACIL 5% CREAM is a generic product labeled by Accord Healthcare Inc., priced at $0.5918 per GM under NDC 16729054235. Its NADAC has been published 218 times since Mar 23, 2022.

FLUOROURACIL 5% CREAM

Fluorouracil
$0.5918per GM

Strength

50 mg/g

NDC

16729054235

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Last Updated

5/20/2026

Active Ingredients

FLUOROURACIL

Approval Type

Generic (ANDA)

FDA Application

ANDA214845

On Market Since

11/11/2021

Pharmacological Classes

Nucleic Acid Synthesis Inhibitors
Nucleoside Metabolic Inhibitor

Price Statistics

The NADAC for FLUOROURACIL 5% CREAM has been published 218 times since Mar 23, 2022, and over the history we have for it it has declined 58.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5918 per GM
All-time high$1.4274 (Apr 13, 2022)
All-time low$0.5918 (May 20, 2026)
52-week high$0.7382
52-week low$0.5918
Median price$0.7382
Average price$0.8080
Largest weekly change+30.8% (Nov 22, 2023)
Weeks tracked218
Tracking sinceMar 23, 2022

Price History

1W

0.0%

1M

0.0%

3M

-1.4%

6M

-4.1%

1Y

-16.9%

3Y

-16.6%

5Y

N/A

All

-58.5%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of FLUOROURACIL 5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for FLUOROURACIL 5% CREAM, manufactured by Accord Healthcare Inc., is $0.5918 per GM (NDC 16729054235), effective May 20, 2026.

How has the price of FLUOROURACIL 5% CREAM changed over time?

Over the history we have for it, the NADAC for FLUOROURACIL 5% CREAM has declined 58.5%. It has been tracked across 218 weekly CMS publications since Mar 23, 2022.

What are the highest and lowest recorded NADAC prices for FLUOROURACIL 5% CREAM?

Since Mar 23, 2022, the NADAC for FLUOROURACIL 5% CREAM has ranged from a low of $0.5918 (May 20, 2026) to a high of $1.4274 (Apr 13, 2022), with a median of $0.7382 per GM.

Are there cheaper alternatives to FLUOROURACIL 5% CREAM?

2 NADAC-published products share the same active ingredient, strength, and dosage form as FLUOROURACIL 5% CREAM, but none are currently priced below it.

Who manufactures FLUOROURACIL 5% CREAM?

FLUOROURACIL 5% CREAM (NDC 16729054235) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.