Product Information
FLUOROURACIL 5% CREAM is a generic product labeled by NorthStar Rx LLC, priced at $0.6034 per GM under NDC 16714017801. Its NADAC has been published 221 times since Jun 1, 2022.
FDA first approved this application on Mar 5, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/g
Manufacturer
NorthStar Rx LLCNDC
16714017801
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
FLUOROURACILApproval Type
Generic (ANDA)
FDA Application
ANDA090368FDA Approved
3/5/2010
TE Code
AB
On Market Since
3/5/2010
Pharmacological Classes
Price Statistics
The NADAC for FLUOROURACIL 5% CREAM has been published 221 times since Jun 1, 2022, and over the history we have for it it has declined 50.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6034 per GM |
|---|---|
| All-time high | $1.2165 (Jun 15, 2022) |
| All-time low | $0.5853 (Jul 22, 2026) |
| 52-week high | $0.7378 |
| 52-week low | $0.5853 |
| Median price | $0.7319 |
| Average price | $0.7728 |
| Largest weekly change | +30.8% (Nov 22, 2023) |
| Weeks tracked | 221 |
| Tracking since | Jun 1, 2022 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of FLUOROURACIL 5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for FLUOROURACIL 5% CREAM, manufactured by NorthStar Rx LLC, is $0.6034 per GM (NDC 16714017801), effective Aug 19, 2026.
How has the price of FLUOROURACIL 5% CREAM changed over time?
Over the history we have for it, the NADAC for FLUOROURACIL 5% CREAM has declined 50.4%. It has been tracked across 221 weekly CMS publications since Jun 1, 2022.
What are the highest and lowest recorded NADAC prices for FLUOROURACIL 5% CREAM?
Since Jun 1, 2022, the NADAC for FLUOROURACIL 5% CREAM has ranged from a low of $0.5853 (Jul 22, 2026) to a high of $1.2165 (Jun 15, 2022), with a median of $0.7319 per GM.
Are there cheaper alternatives to FLUOROURACIL 5% CREAM?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FLUOROURACIL 5% CREAM, is $0.5918 per GM — about 2% below FLUOROURACIL 5% CREAM.
Who manufactures FLUOROURACIL 5% CREAM?
FLUOROURACIL 5% CREAM (NDC 16714017801) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.