Product Information
FLUOROURACIL 5% CREAM is a generic product labeled by NorthStar Rx LLC, priced at $0.6156 per GM under NDC 16714017801. Its NADAC has been published 227 times since Jun 1, 2022.
FDA first approved this application on Mar 5, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/g
Manufacturer
NorthStar Rx LLCNDC
16714017801
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
FLUOROURACILApproval Type
Generic (ANDA)
FDA Application
ANDA090368FDA Approved
3/5/2010
TE Code
AB
On Market Since
3/5/2010
Pharmacological Classes
Price Statistics
The NADAC for FLUOROURACIL 5% CREAM has been published 227 times since Jun 1, 2022, and over the history we have for it it has declined 49.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6156 per GM |
|---|---|
| All-time high | $1.2165 (Jun 15, 2022) |
| All-time low | $0.5853 (Jul 22, 2026) |
| 52-week high | $0.6858 |
| 52-week low | $0.5853 |
| Median price | $0.7319 |
| Average price | $0.7684 |
| Largest weekly change | +30.8% (Nov 22, 2023) |
| Weeks tracked | 227 |
| Tracking since | Jun 1, 2022 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
NorthStar Rx LLC manufacturer profile
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Drug market
Fluorouracil market comparison
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Therapeutic class
Nucleoside Metabolic Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of FLUOROURACIL 5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for FLUOROURACIL 5% CREAM, manufactured by NorthStar Rx LLC, is $0.6156 per GM (NDC 16714017801), effective Sep 30, 2026.
How has the price of FLUOROURACIL 5% CREAM changed over time?
Over the history we have for it, the NADAC for FLUOROURACIL 5% CREAM has declined 49.4%. It has been tracked across 227 weekly CMS publications since Jun 1, 2022.
What are the highest and lowest recorded NADAC prices for FLUOROURACIL 5% CREAM?
Since Jun 1, 2022, the NADAC for FLUOROURACIL 5% CREAM has ranged from a low of $0.5853 (Jul 22, 2026) to a high of $1.2165 (Jun 15, 2022), with a median of $0.7319 per GM.
Are there cheaper alternatives to FLUOROURACIL 5% CREAM?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FLUOROURACIL 5% CREAM, is $0.5918 per GM — about 4% below FLUOROURACIL 5% CREAM.
Who manufactures FLUOROURACIL 5% CREAM?
FLUOROURACIL 5% CREAM (NDC 16714017801) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.