Product Information

GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $0.0335 per EA under NDC 23155023301. Its NADAC has been published 265 times since Nov 28, 2013.

FDA first approved this application on Jun 3, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET

glyburide-metformin hydrochloride
$0.0335per EA

Strength

1.25; 250 mg/1; mg/1

NDC

23155023301

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

5/21/2025

Approval Type

Generic (ANDA)

FDA Application

ANDA079009

FDA Approved

6/3/2009

TE Code

AB

On Market Since

5/1/2024

Pharmacological Classes

Biguanide
Biguanides
Sulfonylurea Compounds
Sulfonylurea

Price Statistics

The NADAC for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET has been published 265 times since Nov 28, 2013, and over the history we have for it it has declined 61.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0335 per EA
All-time high$0.0908 (May 11, 2016)
All-time low$0.0335 (May 21, 2025)
52-week high$0.0335
52-week low$0.0335
Median price$0.0693
Average price$0.0657
Largest weekly change+37.5% (Jun 22, 2016)
Weeks tracked265
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

0.0%

3Y

-27.3%

5Y

-27.3%

All

-61.7%

Last surveyed Dec 10, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET, manufactured by Heritage Pharmaceuticals Inc., is $0.0335 per EA (NDC 23155023301), effective Dec 10, 2025.

How has the price of GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET changed over time?

Over the history we have for it, the NADAC for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET has declined 61.7%. It has been tracked across 265 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET?

Since Nov 28, 2013, the NADAC for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET has ranged from a low of $0.0335 (May 21, 2025) to a high of $0.0908 (May 11, 2016), with a median of $0.0693 per EA.

Are there cheaper alternatives to GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET?

GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET (NDC 23155023301) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.