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Historical record - last NADAC effective date: 11/22/2017

Product Information

GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $0.0461 per EA under NDC 23155023305. Its NADAC has been published 235 times since Nov 28, 2013.

FDA first approved this application on Jun 3, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET

glyburide-metformin hydrochloride
$0.0461per EA

Strength

1.25; 250 mg/1; mg/1

NDC

23155023305

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

11/22/2017

Approval Type

Generic (ANDA)

FDA Application

ANDA079009

FDA Approved

6/3/2009

TE Code

AB

On Market Since

5/1/2024

Pharmacological Classes

Biguanide
Biguanides
Sulfonylurea Compounds
Sulfonylurea

Price Statistics

The NADAC for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET has been published 235 times since Nov 28, 2013, and over the history we have for it it has declined 47.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0461 per EA
All-time high$0.0908 (May 11, 2016)
All-time low$0.0461 (Nov 22, 2017)
Median price$0.0717
Average price$0.0698
Largest weekly change+37.5% (Jun 22, 2016)
Weeks tracked235
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

N/A

5Y

N/A

All

-47.3%

Last surveyed May 23, 2018 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 27% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 27%

1 alternative • Same active ingredient

GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET
Generic
23155023301•Heritage Pharmaceuticals Inc.
$0.0335
Save 27%

Related Drugs

Same classification

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$0.0140
per EA
METFORMIN HCL 500 MG TABLET
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$0.0140
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METFORMIN HCL 500 MG TABLET
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$0.0140
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METFORMIN HCL 500 MG TABLET
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00378718505•Mylan Pharmaceuticals Inc.
$0.0145
per EA
METFORMIN HCL 500 MG TABLET
Generic
00904716261•Major Pharmaceuticals
$0.0145
per EA
METFORMIN HCL 500 MG TABLET
Generic
23155084101•Heritage Pharmaceuticals Inc.
$0.0145
per EA
METFORMIN HCL 500 MG TABLET
Generic
23155084105•Heritage Pharmaceuticals Inc.
$0.0145
per EA
METFORMIN HCL 500 MG TABLET
Generic
23155084110•Heritage Pharmaceuticals Inc.
$0.0145
per EA
METFORMIN HCL 500 MG TABLET
Generic
42385094701•Laurus Labs Limited
$0.0145
per EA
METFORMIN HCL 500 MG TABLET
Generic
42385094705•Laurus Labs Limited
$0.0145
per EA

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Manufacturer

Heritage Pharmaceuticals Inc. manufacturer profile

See the full portfolio, pricing trend, and other products from this labeler.

Drug market

glyburide-metformin hydrochloride market comparison

Compare this molecule across participating manufacturers and inspect the broader market price spread.

Therapeutic class

Biguanide class view

See how this drug behaves alongside other products in the same FDA pharmacologic class.

Trend hub

Latest market trends

Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.

Guide

Understanding NADAC pricing

Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.

Frequently asked questions

What is the NADAC price of GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET, manufactured by Heritage Pharmaceuticals Inc., is $0.0461 per EA (NDC 23155023305), effective May 23, 2018.

How has the price of GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET changed over time?

Over the history we have for it, the NADAC for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET has declined 47.3%. It has been tracked across 235 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET?

Since Nov 28, 2013, the NADAC for GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET has ranged from a low of $0.0461 (Nov 22, 2017) to a high of $0.0908 (May 11, 2016), with a median of $0.0717 per EA.

Are there cheaper alternatives to GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET, is $0.0335 per EA — about 27% below GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET.

Who manufactures GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET?

GLYBURIDE-METFORMIN 1.25 MG-250 MG TABLET (NDC 23155023305) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.