Product Information
DIPHENHYDRAMINE 50 MG/ML VIAL is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $0.9336 per ML under NDC 23155026441. Its NADAC has been published 37 times since Dec 10, 2025.
FDA first approved this application on Jun 24, 2025. Its Orange Book therapeutic-equivalence code is AP.
Strength
50 mg/mL
Manufacturer
Heritage Pharmaceuticals Inc.NDC
23155026441
Classification
Generic
Dosage Form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA205336FDA Approved
6/24/2025
TE Code
AP
On Market Since
6/30/2025
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has been published 37 times since Dec 10, 2025, and over the history we have for it it has risen 2.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9336 per ML |
|---|---|
| All-time high | $0.9459 (Mar 11, 2026) |
| All-time low | $0.9145 (Dec 10, 2025) |
| 52-week high | $0.9459 |
| 52-week low | $0.9145 |
| Median price | $0.9402 |
| Average price | $0.9409 |
| Largest weekly change | +3.0% (Dec 17, 2025) |
| Weeks tracked | 37 |
| Tracking since | Dec 10, 2025 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 50 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 50 MG/ML VIAL, manufactured by Heritage Pharmaceuticals Inc., is $0.9336 per ML (NDC 23155026441), effective Aug 19, 2026.
How has the price of DIPHENHYDRAMINE 50 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has risen 2.1%. It has been tracked across 37 weekly CMS publications since Dec 10, 2025.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 50 MG/ML VIAL?
Since Dec 10, 2025, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has ranged from a low of $0.9145 (Dec 10, 2025) to a high of $0.9459 (Mar 11, 2026), with a median of $0.9402 per ML.
Are there cheaper alternatives to DIPHENHYDRAMINE 50 MG/ML VIAL?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DIPHENHYDRAMINE 50 MG/ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures DIPHENHYDRAMINE 50 MG/ML VIAL?
DIPHENHYDRAMINE 50 MG/ML VIAL (NDC 23155026441) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.