Product Information

DIPHENHYDRAMINE 50 MG/ML VIAL is a generic product labeled by Sagent Pharmaceuticals, priced at $0.9399 per ML under NDC 25021048101. Its NADAC has been published 63 times since Apr 16, 2025.

DIPHENHYDRAMINE 50 MG/ML VIAL

Diphenhydramine Hydrochloride
$0.9399per ML

Strength

50 mg/mL

NDC

25021048101

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRAMUSCULAR; INTRAVENOUS

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA218448

On Market Since

1/15/2025

Pharmacological Classes

Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist

Price Statistics

The NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has been published 63 times since Apr 16, 2025, and over the history we have for it it has risen 3.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.9399 per ML
All-time high$0.9459 (Mar 11, 2026)
All-time low$0.8905 (Sep 17, 2025)
52-week high$0.9459
52-week low$0.8905
Median price$0.9311
Average price$0.9251
Largest weekly change+3.0% (Dec 17, 2025)
Weeks tracked63
Tracking sinceApr 16, 2025

Price History

1W

0.0%

1M

+0.3%

3M

-0.5%

6M

-0.2%

1Y

+1.3%

3Y

N/A

5Y

N/A

All

+3.7%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHENHYDRAMINE 50 MG/ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 50 MG/ML VIAL, manufactured by Sagent Pharmaceuticals, is $0.9399 per ML (NDC 25021048101), effective Jun 24, 2026.

How has the price of DIPHENHYDRAMINE 50 MG/ML VIAL changed over time?

Over the history we have for it, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has risen 3.7%. It has been tracked across 63 weekly CMS publications since Apr 16, 2025.

What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 50 MG/ML VIAL?

Since Apr 16, 2025, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has ranged from a low of $0.8905 (Sep 17, 2025) to a high of $0.9459 (Mar 11, 2026), with a median of $0.9311 per ML.

Are there cheaper alternatives to DIPHENHYDRAMINE 50 MG/ML VIAL?

2 NADAC-published products share the same active ingredient, strength, and dosage form as DIPHENHYDRAMINE 50 MG/ML VIAL, but none are currently priced below it.

Who manufactures DIPHENHYDRAMINE 50 MG/ML VIAL?

DIPHENHYDRAMINE 50 MG/ML VIAL (NDC 25021048101) is labeled by Sagent Pharmaceuticals, and CMS classifies it as a generic product.