Product Information

DIPHEDRYL 12.5 MG/5 ML ELIXIR is a generic product labeled by AmerisourceBergen, priced at $0.0196 per ML under NDC 24385037926. Its NADAC has been published 665 times since Nov 28, 2013.

DIPHEDRYL 12.5 MG/5 ML ELIXIR

Diphenhydramine Hydrochloride
$0.0196per ML
OTC

Strength

12.5 mg/5mL

Manufacturer

AmerisourceBergen

NDC

24385037926

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

8/15/1989

Pharmacological Classes

Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist

Price Statistics

The NADAC for DIPHEDRYL 12.5 MG/5 ML ELIXIR has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 86.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0196 per ML
All-time high$0.0199 (Jul 15, 2026)
All-time low$0.0098 (Nov 23, 2016)
52-week high$0.0199
52-week low$0.0173
Median price$0.0145
Average price$0.0141
Largest weekly change+21.5% (Jun 19, 2024)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-1.1%

1M

-1.1%

3M

-1.3%

6M

+5.0%

1Y

+8.3%

3Y

+22.8%

5Y

+40.3%

All

+86.9%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 27% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHEDRYL 12.5 MG/5 ML ELIXIR?

The current National Average Drug Acquisition Cost (NADAC) for DIPHEDRYL 12.5 MG/5 ML ELIXIR, manufactured by AmerisourceBergen, is $0.0196 per ML (NDC 24385037926), effective Aug 19, 2026.

How has the price of DIPHEDRYL 12.5 MG/5 ML ELIXIR changed over time?

Over the history we have for it, the NADAC for DIPHEDRYL 12.5 MG/5 ML ELIXIR has risen 86.9%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for DIPHEDRYL 12.5 MG/5 ML ELIXIR?

Since Nov 28, 2013, the NADAC for DIPHEDRYL 12.5 MG/5 ML ELIXIR has ranged from a low of $0.0098 (Nov 23, 2016) to a high of $0.0199 (Jul 15, 2026), with a median of $0.0145 per ML.

Are there cheaper alternatives to DIPHEDRYL 12.5 MG/5 ML ELIXIR?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CHILD'S ALLERGY 12.5 MG/5 ML, is $0.0143 per ML — about 27% below DIPHEDRYL 12.5 MG/5 ML ELIXIR.

Who manufactures DIPHEDRYL 12.5 MG/5 ML ELIXIR?

DIPHEDRYL 12.5 MG/5 ML ELIXIR (NDC 24385037926) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.