Product Information
DIPHENHYDRAMINE 12.5 MG/5 ML is a generic product labeled by Oncor Pharmaceuticals, priced at $0.0175 per ML under NDC 83720050216. Its NADAC has been published 67 times since May 14, 2025.
Strength
12.5 mg/5mL
Manufacturer
Oncor PharmaceuticalsNDC
83720050216
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
3/27/2025
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has been published 67 times since May 14, 2025, and over the history we have for it it has risen 44.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0175 per ML |
|---|---|
| All-time high | $0.0178 (Feb 11, 2026) |
| All-time low | $0.0121 (Jun 18, 2025) |
| 52-week high | $0.0178 |
| 52-week low | $0.0122 |
| Median price | $0.0159 |
| Average price | $0.0150 |
| Largest weekly change | +17.4% (Nov 19, 2025) |
| Weeks tracked | 67 |
| Tracking since | May 14, 2025 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 19% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 12.5 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 12.5 MG/5 ML, manufactured by Oncor Pharmaceuticals, is $0.0175 per ML (NDC 83720050216), effective Aug 19, 2026.
How has the price of DIPHENHYDRAMINE 12.5 MG/5 ML changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has risen 44.2%. It has been tracked across 67 weekly CMS publications since May 14, 2025.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 12.5 MG/5 ML?
Since May 14, 2025, the NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has ranged from a low of $0.0121 (Jun 18, 2025) to a high of $0.0178 (Feb 11, 2026), with a median of $0.0159 per ML.
Are there cheaper alternatives to DIPHENHYDRAMINE 12.5 MG/5 ML?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CHILD'S ALLERGY 12.5 MG/5 ML, is $0.0143 per ML — about 19% below DIPHENHYDRAMINE 12.5 MG/5 ML.
Who manufactures DIPHENHYDRAMINE 12.5 MG/5 ML?
DIPHENHYDRAMINE 12.5 MG/5 ML (NDC 83720050216) is labeled by Oncor Pharmaceuticals, and CMS classifies it as a generic product.