Product Information
HYDROQUINONE 4% CREAM is a generic product labeled by Apnar Pharma LP, priced at $0.5358 per GM under NDC 24689010101. Its NADAC has been published 44 times since Sep 27, 2023.
Strength
40 mg/g
Manufacturer
Apnar Pharma LPNDC
24689010101
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
11/19/2025
Active Ingredients
HYDROQUINONEApproval Type
Unapproved
On Market Since
11/1/2021
Pharmacological Classes
Price Statistics
The NADAC for HYDROQUINONE 4% CREAM has been published 44 times since Sep 27, 2023, and over the history we have for it it has declined 17.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5358 per GM |
|---|---|
| All-time high | $0.6616 (Nov 8, 2023) |
| All-time low | $0.5358 (Nov 19, 2025) |
| 52-week high | $0.5419 |
| 52-week low | $0.5358 |
| Median price | $0.5904 |
| Average price | $0.5916 |
| Largest weekly change | -6.2% (Mar 12, 2025) |
| Weeks tracked | 44 |
| Tracking since | Sep 27, 2023 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
-1.1%
3Y
-17.8%
5Y
N/A
All
-17.8%
Last surveyed Nov 19, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 14% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Apnar Pharma LP manufacturer profile
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Drug market
Hydroquinone market comparison
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Therapeutic class
Melanin Synthesis Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROQUINONE 4% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for HYDROQUINONE 4% CREAM, manufactured by Apnar Pharma LP, is $0.5358 per GM (NDC 24689010101), effective Nov 19, 2025.
How has the price of HYDROQUINONE 4% CREAM changed over time?
Over the history we have for it, the NADAC for HYDROQUINONE 4% CREAM has declined 17.8%. It has been tracked across 44 weekly CMS publications since Sep 27, 2023.
What are the highest and lowest recorded NADAC prices for HYDROQUINONE 4% CREAM?
Since Sep 27, 2023, the NADAC for HYDROQUINONE 4% CREAM has ranged from a low of $0.5358 (Nov 19, 2025) to a high of $0.6616 (Nov 8, 2023), with a median of $0.5904 per GM.
Are there cheaper alternatives to HYDROQUINONE 4% CREAM?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROQUINONE 4% CREAM, is $0.4613 per GM — about 14% below HYDROQUINONE 4% CREAM.
Who manufactures HYDROQUINONE 4% CREAM?
HYDROQUINONE 4% CREAM (NDC 24689010101) is labeled by Apnar Pharma LP, and CMS classifies it as a generic product.